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ALKBH8 Antikörper (AA 1-230)

ALKBH8 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6136811
  • Target Alle ALKBH8 Antikörper anzeigen
    ALKBH8 (AlkB, Alkylation Repair Homolog 8 (ALKBH8))
    Bindungsspezifität
    • 15
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 1-230
    Reaktivität
    • 19
    • 16
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 34
    Kaninchen
    Klonalität
    • 34
    Polyklonal
    Konjugat
    • 13
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ALKBH8 Antikörper ist unkonjugiert
    Applikation
    • 13
    • 13
    • 10
    • 8
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    MDSNHQSNYK LSKTEKKFLR KQIKAKHTLL RHEGIETVSY ATQSLVVANG GLGNGVSRNQ LLPVLEKCGL VDALLMPPNK PYSFARYRTT EESKRAYVTL NGKEVVDDLG QKITLYLNFV EKVQWKELRP QALPPGLMVV EEIISSEEEK MLLESVDWTE DTDNQNSQKS LKHRRVKHFG YEFHYENNNV DKDKPLSGGL PDICESFLEK WLRKGYIKHK PDQMTINQYE
    Kreuzreaktivität
    Human, Maus
    Produktmerkmale
    Polyclonal Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human ALKBH8 (NP_620130.2).
    Isotyp
    IgG
  • Applikationshinweise
    WB,1:500 - 1:2000,IHC,1:100 - 1:200
    Kommentare

    HIGH QUALITY

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    ALKBH8 (AlkB, Alkylation Repair Homolog 8 (ALKBH8))
    Andere Bezeichnung
    ALKBH8 (ALKBH8 Produkte)
    Synonyme
    ABH8 antikoerper, 4930562C03Rik antikoerper, 8030431D03Rik antikoerper, 9430088N01Rik antikoerper, Abh8 antikoerper, alkB homolog 8, tRNA methyltransferase antikoerper, ALKBH8 antikoerper, Alkbh8 antikoerper
    Hintergrund
    Catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA via its methyltransferase domain. Catalyzes the last step in the formation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA. Has a preference for tRNA(Arg and tRNA(Glu, and does not bind tRNA(Lys(PubMed:20308323. Binds tRNA and catalyzes the iron and alpha-ketoglutarate dependent hydroxylation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA via its dioxygenase domain, giving rise to 5-(S-methoxycarbonylhydroxymethyluridine, has a preference for tRNA(Gly. Required for normal survival after DNA damage. May inhibit apoptosis and promote cell survival and angiogenesis.,ALKBH8,ABH8,TRM9,TRMT9,Epigenetics & Nuclear Signaling,Cancer,Tumor biomarkers,ALKBH8
    Molekulargewicht
    25 kDa/27 kDa/75 kDa
    Gen-ID
    91801
    UniProt
    Q96BT7
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