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ASAH1 Antikörper (AA 140-389)

ASAH1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6137159
  • Target Alle ASAH1 Antikörper anzeigen
    ASAH1 (N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 (ASAH1))
    Bindungsspezifität
    • 15
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 140-389
    Reaktivität
    • 29
    • 22
    • 6
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 39
    • 5
    Kaninchen
    Klonalität
    • 39
    • 5
    Polyklonal
    Konjugat
    • 20
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ASAH1 Antikörper ist unkonjugiert
    Applikation
    • 33
    • 14
    • 13
    • 13
    • 10
    • 10
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Sequenz
    IVAEDKKGHL IHGRNMDFGV FLGWNINNDT WVITEQLKPL TVNLDFQRNN KTVFKASSFA GYVGMLTGFK PGLFSLTLNE RFSINGGYLG ILEWILGKKD VMWIGFLTRT VLENSTSYEE AKNLLTKTKI LAPAYFILGG NQSGEGCVIT RDRKESLDVY ELDAKQGRWY VVQTNYDRWK HPFFLDDRRT PAKMCLNRTS QENISFETMY DVLSTKPVLN KLTVYTTLID VTKGQFETYL RDCPDPCIGW
    Kreuzreaktivität
    Maus, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 140-389 of human ASAH1 (NP_001120977.1).
    Isotyp
    IgG
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  • Applikationshinweise
    WB,1:500 - 1:2000
    Kommentare

    HIGH QUALITY

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    ASAH1 (N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 (ASAH1))
    Andere Bezeichnung
    ASAH1 (ASAH1 Produkte)
    Synonyme
    AC antikoerper, ACDase antikoerper, ASAH antikoerper, PHP antikoerper, PHP32 antikoerper, SMAPME antikoerper, 2310081N20Rik antikoerper, Asah antikoerper, MGC82286 antikoerper, asah1 antikoerper, zgc:101637 antikoerper, ASAH1 antikoerper, zgc:66026 antikoerper, N-acylsphingosine amidohydrolase 1 antikoerper, N-acylsphingosine amidohydrolase (acid ceramidase) 1 antikoerper, N-acylsphingosine amidohydrolase (acid ceramidase) 1 L homeolog antikoerper, N-acylsphingosine amidohydrolase (acid ceramidase) 1a antikoerper, Acid ceramidase antikoerper, N-acylsphingosine amidohydrolase (acid ceramidase) 1b antikoerper, ASAH1 antikoerper, Asah1 antikoerper, asah1.L antikoerper, asah1a antikoerper, asah-1 antikoerper, asah1b antikoerper
    Hintergrund
    This gene encodes a member of the acid ceramidase family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. Processing of this preproprotein generates alpha and beta subunits that heterodimerize to form the mature lysosomal enzyme, which catalyzes the degradation of ceramide into sphingosine and free fatty acid. This enzyme is overexpressed in multiple human cancers and may play a role in cancer progression. Mutations in this gene are associated with the lysosomal storage disorder, Farber lipogranulomatosis, and a neuromuscular disorder, spinal muscular atrophy with progressive myoclonic epilepsy.,ASAH1,AC,ACDase,ASAH,PHP,PHP32,SMAPME,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,ASAH1
    Molekulargewicht
    44 kDa/46 kDa
    Gen-ID
    427
    UniProt
    Q13510
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