Asialoglycoprotein Receptor 1 Antikörper (AA 1-150)

Produktnummer ABIN6137179

Produktdetails anti-Asialoglycoprotein Receptor 1 Antikörper

Target: Asialoglycoprotein Receptor 1 (ASGR1)

Bindungsspezifität: AA 1-150

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Asialoglycoprotein Receptor 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: MTKEYQDLQH LDNEESDHHQ LRKGPPPPQP LLQRLCSGPR LLLLSLGLSL LLLVVVCVIG SQNSQLQEEL RGLRETFSNF TASTEAQVKG LSTQGGNVGR KMKSLESQLE KQQKDLSEDH SSLLLHVKQF VSDLRSLSCQ MAALQGNGSE

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human ASGR1 (NP_001662.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:1000 - 1:4000,IHC,1:50 - 1:200

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Asialoglycoprotein Receptor 1

Target: Asialoglycoprotein Receptor 1 (ASGR1)

Andere Bezeichnung: ASGR1 (ASGR1 Produkte)

Synonyme: ASGR1 antikoerper, ASGPR antikoerper, ASGPR1 antikoerper, CLEC4H1 antikoerper, HL-1 antikoerper, Asgr antikoerper, Asgr-1 antikoerper, ASGR antikoerper, RATRHL1 antikoerper, RHL1 antikoerper, asialoglycoprotein receptor 1 antikoerper, LOC721786 antikoerper, ASGR1 antikoerper, LOC489461 antikoerper, Asgr1 antikoerper, LOC101116157 antikoerper

Hintergrund: This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the more abundant major subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,ASGR1,ASGPR,ASGPR1,CLEC4H1,HL-1,Signal Transduction,ASGR1

Molekulargewicht: 29 kDa/33 kDa

Gen-ID: 432

UniProt: P07306

Pathways: Thyroid Hormone Synthesis