ASIP Antikörper (AA 23-132)

Produktnummer ABIN6137195

Produktdetails anti-ASIP Antikörper

Target: ASIP (Agouti Signaling Protein (ASIP))

Bindungsspezifität: AA 23-132

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ASIP Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF)

Sequenz: HLPPEEKLRD DRSLRSNSSV NLLDVPSVSI VALNKKSKQI GRKAAEKKRS SKKEASMKKV VRPRTPLSAP CVATRNSCKP PAPACCDPCA SCQCRFFRSA CSCRVLSLNC

Kreuzreaktivität: Human

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 23-132 of human ASIP (NP_001663.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ASIP

Target: ASIP (Agouti Signaling Protein (ASIP))

Andere Bezeichnung: ASIP (ASIP Produkte)

Hintergrund: In mice, the agouti gene encodes a paracrine signaling molecule that causes hair follicle melanocytes to synthesize pheomelanin, a yellow pigment, instead of the black or brown pigment, eumelanin. Pleiotropic effects of constitutive expression of the mouse gene include adult-onset obesity, increased tumor susceptibility, and premature infertility. This gene is highly similar to the mouse gene and encodes a secreted protein that may (1) affect the quality of hair pigmentation, (2) act as a pharmacological antagonist of alpha-melanocyte-stimulating hormone, (3) play a role in neuroendocrine aspects of melanocortin action, and (4) have a functional role in regulating lipid metabolism in adipocytes.,ASIP,AGSW,AGTI,AGTIL,ASP,SHEP9,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,Neuroscience,ASIP

Molekulargewicht: 14 kDa

Gen-ID: 434

UniProt: P42127

Pathways: Cell-Cell Junction Organization, Feeding Behaviour