Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

AXIN2 Antikörper (AA 650-750)

AXIN2 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6137382
  • Target Alle AXIN2 Antikörper anzeigen
    AXIN2 (Axin 2 (AXIN2))
    Bindungsspezifität
    • 15
    • 14
    • 11
    • 8
    • 7
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 650-750
    Reaktivität
    • 70
    • 53
    • 40
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Human
    Wirt
    • 83
    • 2
    Kaninchen
    Klonalität
    • 74
    • 11
    Polyklonal
    Konjugat
    • 24
    • 8
    • 8
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser AXIN2 Antikörper ist unkonjugiert
    Applikation
    • 62
    • 37
    • 30
    • 14
    • 13
    • 13
    • 6
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Sequenz
    RSSPGERASR HHLWGGNSGH PRTTPRAHLF TQDPAMPPLT PPNTLAQLEE ACRRLAEVSK PPKQRCCVAS QQRDRNHSAT VQTGATPFSN PSLAPEDHKE P
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    A synthetic peptide corresponding to a sequence within amino acids 650-750 of human AXIN2 (NP_004646.3).
    Isotyp
    IgG
  • Applikationshinweise
    WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Chen, Zheng, Liu, Shi, Qi: "Periostin activates pathways involved in epithelial-mesenchymal transition in adamantinomatous craniopharyngioma." in: Journal of the neurological sciences, Vol. 360, pp. 49-54, (2016) (PubMed).

  • Target
    AXIN2 (Axin 2 (AXIN2))
    Andere Bezeichnung
    AXIN2 (AXIN2 Produkte)
    Synonyme
    AXIL antikoerper, ODCRCS antikoerper, axil antikoerper, wu:fb37c08 antikoerper, zgc:111942 antikoerper, axin-2 antikoerper, xarp antikoerper, MGC81576 antikoerper, arp-A antikoerper, axin2 antikoerper, Axi1 antikoerper, Axil antikoerper, Conductin antikoerper, axin 2 antikoerper, axin 2 (conductin, axil) antikoerper, axin 2 (conductin, axil) S homeolog antikoerper, AXIN2 antikoerper, axin2 antikoerper, axin2.S antikoerper, Axin2 antikoerper
    Hintergrund
    The Axin-related protein, Axin2, presumably plays an important role in the regulation of the stability of beta-catenin in the Wnt signaling pathway, like its rodent homologs, mouse conductin/rat axil. In mouse, conductin organizes a multiprotein complex of APC (adenomatous polyposis of the colon), beta-catenin, glycogen synthase kinase 3-beta, and conductin, which leads to the degradation of beta-catenin. Apparently, the deregulation of beta-catenin is an important event in the genesis of a number of malignancies. The AXIN2 gene has been mapped to 17q23-q24, a region that shows frequent loss of heterozygosity in breast cancer, neuroblastoma, and other tumors. Mutations in this gene have been associated with colorectal cancer with defective mismatch repair.,AXIN2,AXIL,ODCRCS,axin-2,Epigenetics & Nuclear Signaling,Cancer,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Cell differentiation,Wnt/β-Catenin Signaling Pathway,ESC Pluripotency and Differentiation,Neuroscience,Stem Cells,AXIN2
    Molekulargewicht
    93 kDa
    Gen-ID
    8313
    UniProt
    Q9Y2T1
    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling
Sie sind hier:
Kundenservice