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BARD1 Antikörper

BARD1 Reaktivität: Maus WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6137449
  • Target Alle BARD1 Antikörper anzeigen
    BARD1 (BRCA1 Associated RING Domain 1 (BARD1))
    Reaktivität
    • 52
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 49
    • 3
    Kaninchen
    Klonalität
    • 49
    • 3
    Polyklonal
    Konjugat
    • 18
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser BARD1 Antikörper ist unkonjugiert
    Applikation
    • 42
    • 21
    • 14
    • 13
    • 13
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant protein of mouse BARD1
    Isotyp
    IgG
    Top Product
    Discover our top product BARD1 Primärantikörper
  • Applikationshinweise
    WB,1:500 - 1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    BARD1 (BRCA1 Associated RING Domain 1 (BARD1))
    Andere Bezeichnung
    BARD1 (BARD1 Produkte)
    Synonyme
    BARD1 antikoerper, LOC100147913 antikoerper, ENSMUSG00000060893 antikoerper, ENSMUSG00000073653 antikoerper, BRCA1 associated RING domain 1 antikoerper, BARD1 antikoerper, bard1 antikoerper, Bard1 antikoerper
    Hintergrund
    This gene encodes a protein which interacts with the N-terminal region of BRCA1. In addition to its ability to bind BRCA1 in vivo and in vitro, it shares homology with the 2 most conserved regions of BRCA1: the N-terminal RING motif and the C-terminal BRCT domain. The RING motif is a cysteine-rich sequence found in a variety of proteins that regulate cell growth, including the products of tumor suppressor genes and dominant protooncogenes. This protein also contains 3 tandem ankyrin repeats. The BARD1/BRCA1 interaction is disrupted by tumorigenic amino acid substitutions in BRCA1, implying that the formation of a stable complex between these proteins may be an essential aspect of BRCA1 tumor suppression. This protein may be the target of oncogenic mutations in breast or ovarian cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.,BARD1,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Cancer,Tumor suppressors,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Ubiquitin,Endocrine & Metabolism,BARD1
    Molekulargewicht
    14 kDa/75 kDa/84 kDa/86 kDa
    Gen-ID
    12021
    Pathways
    DNA Reparatur
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