C10orf2 Antikörper (AA 385-684)

Produktnummer ABIN6137715

Produktdetails anti-C10orf2 Antikörper

Target: C10orf2 (C10ORF2) (Chromosome 10 Open Reading Frame 2 (C10ORF2))

Bindungsspezifität: AA 385-684

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C10orf2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: EQAAGLRWSR FPDLNRILKG HRKGELTVFT GPTGSGKTTF ISEYALDLCS QGVNTLWGSF EISNVRLARV MLTQFAEGRL EDQLDKYDHW ADRFEDLPLY FMTFHGQQSI RTVIDTMQHA VYVYDICHVI IDNLQFMMGH EQLSTDRIAA QDYIIGVFRK FATDNNCHVT LVIHPRKEDD DKELQTASIF GSAKASQEAD NVLILQDRKL VTGPGKRYLQ VSKNRFDGDV GVFPLEFNKN SLTFSIPPKN KARLKKIKDD TGPVAKKPSS GKKGATTQNS EICSGQAPTP DQPDTSKRSK

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 385-684 of human C10orf2 (NP_068602.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu C10orf2

Target: C10orf2 (C10ORF2) (Chromosome 10 Open Reading Frame 2 (C10ORF2))

Andere Bezeichnung: TWNK (C10ORF2 Produkte)

Hintergrund: This gene encodes a hexameric DNA helicase which unwinds short stretches of double-stranded DNA in the 5' to 3' direction and, along with mitochondrial single-stranded DNA binding protein and mtDNA polymerase gamma, is thought to play a key role in mtDNA replication. The protein localizes to the mitochondrial matrix and mitochondrial nucleoids. Mutations in this gene cause infantile onset spinocerebellar ataxia (IOSCA) and progressive external ophthalmoplegia (PEO) and are also associated with several mitochondrial depletion syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms.,TWNK,ATXN8,C10orf2,IOSCA,MTDPS7,PEO,PEO1,PEOA3,PRLTS5,SANDO,SCA8,TWINL,Epigenetics & Nuclear Signaling,Endocrine & Metabolism,Mitochondrial metabolism,Neuroscience,Neurodegenerative Diseases,TWNK

Molekulargewicht: 60 kDa/66 kDa/77 kDa

Gen-ID: 56652

UniProt: Q96RR1