C1R Antikörper (AA 466-705)

Produktnummer ABIN6137761

Produktdetails anti-C1R Antikörper

Target: C1R (Complement Component 1, R Subcomponent (C1R))

Bindungsspezifität: AA 466-705

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C1R Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Sequenz: GGQKAKMGNF PWQVFTNIHG RGGGALLGDR WILTAAHTLY PKEHEAQSNA SLDVFLGHTN VEELMKLGNH PIRRVSVHPD YRQDESYNFE GDIALLELEN SVTLGPNLLP ICLPDNDTFY DLGLMGYVSG FGVMEEKIAH DLRFVRLPVA NPQACENWLR GKNRMDVFSQ NMFCAGHPSL KQDACQGDSG GVFAVRDPNT DRWVATGIVS WGIGCSRGYG FYTKVLNYVD WIKKEMEEED

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 466-705 of human C1R (NP_001724.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu C1R

Target: C1R (Complement Component 1, R Subcomponent (C1R))

Andere Bezeichnung: C1R (C1R Produkte)

Synonyme: C1R antikoerper, MGC84776 antikoerper, MGC127774 antikoerper, c1rl antikoerper, complement C1r antikoerper, complement component 1, r subcomponent L homeolog antikoerper, complement component 1, r subcomponent antikoerper, C1R antikoerper, C1r antikoerper, c1r.L antikoerper, c1r antikoerper

Hintergrund: The classical complement pathway plays a major role in innate immunity against infection. This pathway is triggered by C1, a multimolecular complex composed of the recognition protein C1q and two serine proteases, C1r and C1s. Following the C1q recognition, C1r is autoactivated, and in turn activates C1s, which cleaves C4 and C2, the C1 substrates. C1r acts by transforming the activation signal into an enzymic activity. C1r is a single-chain glycoprotein which can be cleaved into an A chain and a B chain upon activation. This protien recognizes full-length C1r chain and the cleaved B chain.,C1R,EDSPD1,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,C1R

Molekulargewicht: 80 kDa

Gen-ID: 715

UniProt: P00736

Pathways: Komplementsystem