CAMLG Antikörper (AA 1-190)

Produktnummer ABIN6137896

Produktdetails anti-CAMLG Antikörper

Target: CAMLG (Calcium Modulating Ligand (CAMLG))

Bindungsspezifität: AA 1-190

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CAMLG Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequenz: MESMAVATDG GERPGVPAGS GLSASQRRAE LRRRKLLMNS EQRINRIMGF HRPGSGAEEE SQTKSKQQDS DKLNSLSVPS VSKRVVLGDS VSTGTTDQQG GVAEVKGTQL GDKLDSFIKP PECSSDVNLE LRQRNRGDLT ADSVQRGSRH GLEQYLSRFE EAMKLRKQLI SEKPSQEDGN TTEEFDSFRI

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human CAMLG (NP_001736.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CAMLG

Target: CAMLG (Calcium Modulating Ligand (CAMLG))

Andere Bezeichnung: CAMLG (CAMLG Produkte)

Synonyme: MGC53900 antikoerper, CAML antikoerper, AI385748 antikoerper, Camlg antikoerper, Caml antikoerper, calcium modulating ligand L homeolog antikoerper, calcium modulating ligand antikoerper, camlg.L antikoerper, CAMLG antikoerper, camlg antikoerper, Caml antikoerper, Camlg antikoerper

Hintergrund: The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin.,CAMLG,CAML,GET2,Signal Transduction,Neuroscience,Calcium Signaling,CAMLG

Molekulargewicht: 32 kDa

Gen-ID: 819

UniProt: P49069

Pathways: EGFR Signaling Pathway