CARD10 Antikörper (AA 863-1032)

Produktnummer ABIN6137937

Produktdetails anti-CARD10 Antikörper

Target: CARD10 (Caspase Recruitment Domain Family, Member 10 (CARD10))

Bindungsspezifität: AA 863-1032

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CARD10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequenz: LLDLPSSRLD FQVCPAESLS GEELCPSSAP GAPKAQPATP GLGSRIRAIQ ESVGKKHCLL ELGARGVREL VQNEIYPIVI HVEVTEKNVR EVRGLLGRPG WRDSELLRQC RGSEQVLWGL PCSWVQVPAH EWGHAEELAK VVRGRILQEQ ARLVWVECGS SRGCPSSSEA

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 863-1032 of human CARD10 (NP_055365.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CARD10

Target: CARD10 (Caspase Recruitment Domain Family, Member 10 (CARD10))

Andere Bezeichnung: CARD10 (CARD10 Produkte)

Hintergrund: The caspase recruitment domain (CARD) is a protein module that consists of 6 or 7 antiparallel alpha helices. It participates in apoptosis signaling through highly specific protein-protein homophilic interactions. Like several other CARD proteins, CARD10 belongs to the membrane-associated guanylate kinase (MAGUK) family and activates NF-kappa-B (NFKB, see MIM 164011) through BCL10 (MIM 603517) (Wang et al., 2001 [PubMed 11259443]).[supplied by OMIM, Mar 2008],CARD10,BIMP1,CARMA3,Cell Biology & Developmental Biology,Apoptosis,Caspases,CARD10

Molekulargewicht: 82 kDa/115 kDa

Gen-ID: 29775

UniProt: Q9BWT7

Pathways: S100 Proteine