CARD11 Antikörper (AA 985-1154)

Produktnummer ABIN6137939

Produktdetails anti-CARD11 Antikörper

Target: CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))

Bindungsspezifität: AA 985-1154

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CARD11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Sequenz: AKTLVQRLLN SGGAMEFTIC KSDIVTRDEF LRRQKTETII YSREKNPNAF ECIAPANIEA VAAKNKHCLL EAGIGCTRDL IKSNIYPIVL FIRVCEKNIK RFRKLLPRPE TEEEFLRVCR LKEKELEALP CLYATVEPDM WGSVEELLRV VKDKIGEEQR KTIWVDEDQL

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 985-1154 of human CARD11 (NP_115791.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:100

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CARD11

Target: CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))

Andere Bezeichnung: CARD11 (CARD11 Produkte)

Synonyme: BENTA antikoerper, BIMP3 antikoerper, CARMA1 antikoerper, PPBL antikoerper, 0610008L17Rik antikoerper, 2410011D02Rik antikoerper, CARD11 antikoerper, LOC100232755 antikoerper, caspase recruitment domain family member 11 antikoerper, caspase recruitment domain family, member 11 antikoerper, caspase recruitment domain-containing protein 11 antikoerper, CARD11 antikoerper, Card11 antikoerper, LOC100550812 antikoerper, card11 antikoerper

Hintergrund: The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10.,CARD11,BENTA,BIMP3,CARMA1,IMD11,PPBL,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Caspases,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,CARD11

Molekulargewicht: 133 kDa

Gen-ID: 84433

UniProt: Q9BXL7

Pathways: T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, BCR Signaling