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CD22 Antikörper (AA 708-847)

CD22 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6138143
  • Target Alle CD22 Antikörper anzeigen
    CD22 (CD22 Molecule (CD22))
    Bindungsspezifität
    • 16
    • 11
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 708-847
    Reaktivität
    • 143
    • 52
    • 24
    • 5
    • 3
    • 2
    • 2
    • 1
    Human
    Wirt
    • 91
    • 61
    • 16
    Kaninchen
    Klonalität
    • 116
    • 54
    Polyklonal
    Konjugat
    • 83
    • 15
    • 13
    • 11
    • 8
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD22 Antikörper ist unkonjugiert
    Applikation
    • 103
    • 72
    • 45
    • 37
    • 36
    • 20
    • 13
    • 12
    • 11
    • 8
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Sequenz
    LQRRWKRTQS QQGLQENSSG QSFFVRNKKV RRAPLSEGPH SLGCYNPMME DGISYTTLRF PEMNIPRTGD AESSEMQRPP PDCDDTVTYS ALHKRQVGDY ENVIPDFPED EGIHYSELIQ FGVGERPQAQ ENVDYVILKH
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 708-847 of human CD22 (NP_001762.2).
    Isotyp
    IgG
    Top Product
    Discover our top product CD22 Primärantikörper
  • Applikationshinweise
    WB,1:500 - 1:2000,IF,1:10 - 1:100
    Kommentare

    HIGH QUALITY

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    CD22 (CD22 Molecule (CD22))
    Andere Bezeichnung
    CD22 (CD22 Produkte)
    Synonyme
    A530093D23 antikoerper, Lyb-8 antikoerper, Lyb8 antikoerper, SIGLEC-2 antikoerper, SIGLEC2 antikoerper, siglec-2 antikoerper, CD22 antigen antikoerper, CD22 molecule antikoerper, Cd22 antikoerper, CD22 antikoerper
    Hintergrund
    Siglecs (sialic acid binding Ig-like lectins) are I-type (Ig-type) lectins belonging to the Ig superfamily. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by varying numbers of Ig-like C2-type domains. Human Siglec-2, also known as B-cell antigen CD22 or Blymphocyte cell adhesion molecule (BL-CAM), is a B-cell restricted glycoprotein that is expressed in the cytoplasm of progenitor B and pre-B cells and on the surface of mature B cells. Two distinct human Siglec2/CD22 cDNAs that arise from differential RNA processing of the same gene have been isolated. Siglec2/CD22 is an adhesion molecule that preferentially binds alpha 2,6- linked sialic acid on the same (cis) or adjacent (trans) cells. Interaction of CD22 with trans ligands on opposing cells was found to be favored over the binding of ligands in cis.,CD22,SIGLEC-2,SIGLEC2,Cancer,Tumor immunology,Tumor-associated antigens,Tumor biomarkers,Immunology & Inflammation,CD markers,B Cell Receptor Signaling Pathway,Stem Cells,Hematopoietic Progenitors,CD22
    Molekulargewicht
    75 kDa/84 kDa/85 kDa/95 kDa
    Gen-ID
    933
    UniProt
    P20273
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