CEMIP Antikörper (AA 180-420)
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- Target Alle CEMIP Antikörper anzeigen
- CEMIP (Cell Migration Inducing Hyaluronan Binding Protein (CEMIP))
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Bindungsspezifität
- AA 180-420
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CEMIP Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- FERSWGHRGV IVHVIDPKSG TVIHSDRFDT YRSKKESERL VQYLNAVPDG RILSVAVNDE GSRNLDDMAR KAMTKLGSKH FLHLGFRHPW SFLTVKGNPS SSVEDHIEYH GHRGSAAARV FKLFQTEHGE YFNVSLSSEW VQDVEWTEWF DHDKVSQTKG GEKISDLWKA HPGKICNRPI DIQATTMDGV NLSTEVVYKK GQDYRFACYD RGRACRSYRV RFLCGKPVRP KLTVTIDTNV N
- Kreuzreaktivität
- Human, Maus
- Produktmerkmale
- Polyclonal Antibodies
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 180-420 of human CEMIP (NP_061159.1).
- Isotyp
- IgG
- Top Product
- Discover our top product CEMIP Primärantikörper
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- Applikationshinweise
- WB,1:500 - 1:2000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- CEMIP (Cell Migration Inducing Hyaluronan Binding Protein (CEMIP))
- Andere Bezeichnung
- CEMIP (CEMIP Produkte)
- Hintergrund
- Mediates depolymerization of hyaluronic acid (HA via the cell membrane-associated clathrin-coated pit endocytic pathway. Binds to hyaluronic acid. Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product, a process that may occur through rapid vesicle endocytosis and recycling without intracytoplasmic accumulation or digestion in lysosomes. Involved in hyaluronan catabolism in the dermis of the skin and arthritic synovium. Positively regulates epithelial-mesenchymal transition (EMT, and hence tumor cell growth, invasion and cancer dissemination. In collaboration with HSPA5/BIP, promotes cancer cell migration in a calcium and PKC-dependent manner. May be involved in hearing.,CEMIP,CCSP1,HYBID,KIAA1199,TMEM2L,Cancer,Tumor suppressors,Neuroscience,CEMIP
- Molekulargewicht
- 110 kDa/152 kDa
- Gen-ID
- 57214
- UniProt
- Q8WUJ3
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