CISH Antikörper (AA 1-257)

Produktnummer ABIN6138639

Produktdetails anti-CISH Antikörper

Target: CISH (Cytokine Inducible SH2-Containing Protein (CISH))

Bindungsspezifität: AA 1-257

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CISH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MVLCVQGPRP LLAVERTGQR PLWAPSLELP KPVMQPLPAG AFLEEVAEGT PAQTESEPKV LDPEEDLLCI AKTFSYLRES GWYWGSITAS EARQHLQKMP EGTFLVRDST HPSYLFTLSV KTTRGPTNVR IEYADSSFRL DSNCLSRPRI LAFPDVVSLV QHYVASCTAD TRSDSPDPAP TPALPMPKED APSDPALPAP PPATAVHLKL VQPFVRRSSA RSLQHLCRLV INRLVADVDC LPLPRRMADY LRQYPFQ

Kreuzreaktivität: Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-257 of human CISH (NP_659508.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CISH

Target: CISH (Cytokine Inducible SH2-Containing Protein (CISH))

Andere Bezeichnung: CISH (CISH Produkte)

Synonyme: CISH antikoerper, cis antikoerper, cish.a antikoerper, ptk9l antikoerper, twf1l antikoerper, wu:fk57g04 antikoerper, zgc:154062 antikoerper, zgc:91817 antikoerper, g18 antikoerper, socs antikoerper, cis-1 antikoerper, cish antikoerper, BACTS2 antikoerper, CIS antikoerper, CIS-1 antikoerper, G18 antikoerper, SOCS antikoerper, AI385595 antikoerper, CIS1 antikoerper, Cis antikoerper, F17 antikoerper, F23 antikoerper, cytokine inducible SH2 containing protein antikoerper, cytokine inducible SH2-containing protein antikoerper, CISH antikoerper, cish antikoerper, Cish antikoerper

Hintergrund: The protein encoded by this gene contains a SH2 domain and a SOCS box domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by IL2, IL3, GM-CSF and EPO in hematopoietic cells. Proteasome-mediated degradation of this protein has been shown to be involved in the inactivation of the erythropoietin receptor. Multiple transcript variants encoding different isoforms have been found for this gene.,CISH,BACTS2,CIS,CIS-1,G18,SOCS,Epigenetics & Nuclear Signaling,Signal Transduction,Immunology & Inflammation,IL-6 Receptor Signaling Pathway,CISH

Molekulargewicht: 28 kDa/29 kDa/30 kDa

Gen-ID: 1154

UniProt: Q9NSE2

Pathways: JAK-STAT Signalweg, Response to Growth Hormone Stimulus