CKAP5 Antikörper (AA 1763-2032)

Produktnummer ABIN6138647

Produktdetails anti-CKAP5 Antikörper

Target: CKAP5 (Cytoskeleton Associated Protein 5 (CKAP5))

Bindungsspezifität: AA 1763-2032

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CKAP5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF)

Sequenz: LLHTLCKLKG PKILDHLTMI DNKNESELEA HLCRMMKHSM DQTGSKSDKE TEKGASRIDE KSSKAKVNDF LAEIFKKIGS KENTKEGLAE LYEYKKKYSD ADIEPFLKNS SQFFQSYVER GLRVIEMERE GKGRISTSTG ISPQMEVTCV PTPTSTVSSI GNTNGEEVGP SVYLERLKIL RQRCGLDNTK QDDRPPLTSL LSKPAVPTVA SSTDMLHSKL SQLRESREQH QHSDLDSNQT HSSGTVTSSS STANIDDLKK RLERIKSSRK

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1763-2032 of human CKAP5 (NP_001008938.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200,IP,1:50 - 1:200

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CKAP5

Target: CKAP5 (Cytoskeleton Associated Protein 5 (CKAP5))

Andere Bezeichnung: CKAP5 (CKAP5 Produkte)

Hintergrund: This gene encodes a cytoskeleton-associated protein which belongs to the TOG/XMAP215 family. The N-terminal half of this protein contains a microtubule-binding domain and the C-terminal half contains a KXGS motif for binding tubulin dimers. This protein has two distinct roles in spindle formation, it protects kinetochore microtubules from depolymerization and plays an essential role in centrosomal microtubule assembly. This protein may be necessary for the proper interaction of microtubules with the cell cortex for directional cell movement. It also plays a role in translation of the myelin basic protein (MBP) mRNA by interacting with heterogeneous nuclear ribonucleoprotein (hnRNP) A2, which associates with MBP. Alternatively spliced transcript variants encoding different isoforms have been identified.,CKAP5,CHTOG,MSPS,TOG,TOGp,ch-TOG,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Cytoskeleton,Microtubules,CKAP5

Molekulargewicht: 218 kDa/225 kDa/226 kDa

Gen-ID: 9793

UniProt: Q14008

Pathways: M Phase