CLK2 Antikörper (AA 239-498)

Produktnummer ABIN6138733

Produktdetails anti-CLK2 Antikörper

Target: CLK2 (CDC-Like Kinase 2 (CLK2))

Bindungsspezifität: AA 239-498

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CLK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: CISFELLGLS TFDFLKDNNY LPYPIHQVRH MAFQLCQAVK FLHDNKLTHT DLKPENILFV NSDYELTYNL EKKRDERSVK STAVRVVDFG SATFDHEHHS TIVSTRHYRA PEVILELGWS QPCDVWSIGC IIFEYYVGFT LFQTHDNREH LAMMERILGP IPSRMIRKTR KQKYFYRGRL DWDENTSAGR YVRENCKPLR RYLTSEAEEH HQLFDLIESM LEYEPAKRLT LGEALQHPFF ARLRAEPPNK LWDSSRDISR

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 239-498 of human CLK2 (NP_003984.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CLK2

Target: CLK2 (CDC-Like Kinase 2 (CLK2))

Andere Bezeichnung: CLK2 (CLK2 Produkte)

Hintergrund: This gene encodes a dual specificity protein kinase that phosphorylates serine/threonine and tyrosine-containing substrates. Activity of this protein regulates serine- and arginine-rich (SR) proteins of the spliceosomal complex, thereby influencing alternative transcript splicing. Chromosomal translocations have been characterized between this locus and the PAFAH1B3 (platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29 kDa)) gene on chromosome 19, resulting in the production of a fusion protein. Note that this gene is distinct from the TELO2 gene (GeneID:9894), which shares the CLK2 alias, but encodes a protein that is involved in telomere length regulation. There is a pseudogene for this gene on chromosome 7. Alternative splicing results in multiple transcript variants.,CLK2,Epigenetics & Nuclear Signaling,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Cell Cycle,CLK2

Molekulargewicht: 17 kDa/59 kDa/60 kDa

Gen-ID: 1196

UniProt: P49760

Pathways: Regulation of Carbohydrate Metabolic Process