CLPS Antikörper (AA 18-112)

Produktnummer ABIN6138743

Produktdetails anti-CLPS Antikörper

Target: CLPS (Colipase, Pancreatic (CLPS))

Bindungsspezifität: AA 18-112

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CLPS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: APGPRGIIIN LENGELCMNS AQCKSNCCQH SSALGLARCT SMASENSECS VKTLYGIYYK CPCERGLTCE GDKTIVGSIT NTNFGICHDA GRSKQ

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 18-112 of human CLPS (NP_001823.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CLPS

Target: CLPS (Colipase, Pancreatic (CLPS))

Andere Bezeichnung: CLPS (CLPS Produkte)

Synonyme: CLPS antikoerper, 2200003J09Rik antikoerper, COLQ antikoerper, colipase antikoerper, colipase, pancreatic antikoerper, CLPS antikoerper, Clps antikoerper

Hintergrund: The protein encoded by this gene is a cofactor needed by pancreatic lipase for efficient dietary lipid hydrolysis. It binds to the C-terminal, non-catalytic domain of lipase, thereby stabilizing an active conformation and considerably increasing the overall hydrophobic binding site. The gene product allows lipase to anchor noncovalently to the surface of lipid micelles, counteracting the destabilizing influence of intestinal bile salts. This cofactor is only expressed in pancreatic acinar cells, suggesting regulation of expression by tissue-specific elements. Three transcript variants encoding different isoforms have been found for this gene.,CLPS,colipase,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Lipases,Cardiovascular,Lipids,CLPS

Molekulargewicht: 11 kDa

Gen-ID: 1208

UniProt: P04118

Pathways: Lipid Metabolism