Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

CNOT1 Antikörper (AA 2137-2376)

CNOT1 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6138777
  • Target Alle CNOT1 Antikörper anzeigen
    CNOT1 (CCR4-NOT Transcription Complex, Subunit 1 (CNOT1))
    Bindungsspezifität
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    AA 2137-2376
    Reaktivität
    • 16
    • 2
    • 1
    Human
    Wirt
    • 15
    • 1
    Kaninchen
    Klonalität
    • 16
    Polyklonal
    Konjugat
    • 9
    • 3
    • 2
    • 2
    Dieser CNOT1 Antikörper ist unkonjugiert
    Applikation
    • 13
    • 6
    • 5
    • 2
    • 2
    Western Blotting (WB), Immunofluorescence (IF)
    Sequenz
    PRNMRLPDPF TPNLKVDMLS EINIAPRILT NFTGVMPPQF KKDLDSYLKT RSPVTFLSDL RSNLQVSNEP GNRYNLQLIN ALVLYVGTQA IAHIHNKGST PSMSTITHSA HMDIFQNLAV DLDTEGRYLF LNAIANQLRY PNSHTHYFSC TMLYLFAEAN TEAIQEQITR VLLERLIVNR PHPWGLLITF IELIKNPAFK FWNHEFVHCA PEIEKLFQSV AQCCMGQKQA QQVMEGTGAS
    Kreuzreaktivität
    Human, Maus
    Produktmerkmale
    Polyclonal Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 2137-2376 of human CNOT1 (NP_057368.3).
    Isotyp
    IgG
    Top Product
    Discover our top product CNOT1 Primärantikörper
  • Applikationshinweise
    WB,1:200 - 1:2000,IF,1:50 - 1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    CNOT1 (CCR4-NOT Transcription Complex, Subunit 1 (CNOT1))
    Andere Bezeichnung
    CNOT1 (CNOT1 Produkte)
    Synonyme
    CDC39 antikoerper, NOT1 antikoerper, NOT1H antikoerper, 6030411K04Rik antikoerper, AA815922 antikoerper, D830048B13 antikoerper, RGD1308009 antikoerper, GB18988 antikoerper, cdc39-like antikoerper, im:7141761 antikoerper, kiaa1007l antikoerper, wu:fc58h04 antikoerper, zgc:152902 antikoerper, CNOT1 antikoerper, not1 antikoerper, cdc39 antikoerper, not1h antikoerper, ad-005 antikoerper, NV18106 antikoerper, CCR4-NOT transcription complex subunit 1 antikoerper, CCR4-NOT transcription complex, subunit 1 antikoerper, CNOT1 antikoerper, Cnot1 antikoerper, LOC412371 antikoerper, cnot1 antikoerper, LOC100114396 antikoerper
    Hintergrund
    Scaffolding component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Its scaffolding function implies its interaction with the catalytic complex module and diverse RNA-binding proteins mediating the complex recruitment to selected mRNA 3'UTRs. Involved in degradation of AU-rich element (ARE-containing mRNAs probably via association with ZFP36. Mediates the recruitment of the CCR4-NOT complex to miRNA targets and to the RISC complex via association with TNRC6A, TNRC6B or TNRC6C. Acts as a transcriptional repressor. Represses the ligand-dependent transcriptional activation by nuclear receptors. Involved in the maintenance of embryonic stem (ES cell identity.,CNOT1,AD-005,CDC39,NOT1,NOT1H,Epigenetics & Nuclear Signaling,RNA Binding,CNOT1
    Molekulargewicht
    173 kDa/241 kDa/266 kDa
    Gen-ID
    23019
    UniProt
    A5YKK6
    Pathways
    Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Stem Cell Maintenance
Sie sind hier:
Kundenservice