CNOT8 Antikörper (AA 1-292)

Produktnummer ABIN6138786

Produktdetails anti-CNOT8 Antikörper

Target: CNOT8 (CCR4-NOT Transcription Complex, Subunit 8 (CNOT8))

Bindungsspezifität: AA 1-292

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CNOT8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MPAALVENSQ VICEVWASNL EEEMRKIREI VLSYSYIAMD TEFPGVVVRP IGEFRSSIDY QYQLLRCNVD LLKIIQLGLT FTNEKGEYPS GINTWQFNFK FNLTEDMYSQ DSIDLLANSG LQFQKHEEEG IDTLHFAELL MTSGVVLCDN VKWLSFHSGY DFGYMVKLLT DSRLPEEEHE FFHILNLFFP SIYDVKYLMK SCKNLKGGLQ EVADQLDLQR IGRQHQAGSD SLLTGMAFFR MKELFFEDSI DDAKYCGRLY GLGTGVAQKQ NEDVDSAQEK MSILAIINNM QQ

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-292 of human CNOT8 (NP_004770.4).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CNOT8

Target: CNOT8 (CCR4-NOT Transcription Complex, Subunit 8 (CNOT8))

Andere Bezeichnung: CNOT8 (CNOT8 Produkte)

Synonyme: calif antikoerper, pop2 antikoerper, zgc:63844 antikoerper, wu:fe49a05 antikoerper, caf1 antikoerper, hcaf1 antikoerper, CAF1 antikoerper, CALIF antikoerper, Caf1b antikoerper, POP2 antikoerper, hCAF1 antikoerper, 1500015I04Rik antikoerper, 1810022F04Rik antikoerper, AA536816 antikoerper, AU015770 antikoerper, AU043059 antikoerper, CCR4-NOT transcription complex, subunit 8 antikoerper, CCR4-NOT transcription complex subunit 8 antikoerper, CCR4-NOT transcription complex subunit 8 S homeolog antikoerper, Cnot8 antikoerper, CNOT8 antikoerper, cnot8.S antikoerper, cnot8 antikoerper, PAAG_04884 antikoerper, VDBG_08730 antikoerper

Hintergrund: Has 3'-5' poly(A exoribonuclease activity for synthetic poly(A RNA substrate. Its function seems to be partially redundant with that of CNOT7. Catalytic component of the CCR4-NOT complex which is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation. Additional complex functions may be a consequence of its influence on mRNA expression. Associates with members of the BTG family such as TOB1 and BTG2 and is required for their anti-proliferative activity.,CNOT8,CAF1,CALIF,Caf1b,POP2,hCAF1,Epigenetics & Nuclear Signaling,Transcription Factors,CNOT8

Molekulargewicht: 21 kDa/27 kDa/33 kDa

Gen-ID: 9337

UniProt: Q9UFF9