COASY Antikörper (AA 345-564)

Produktnummer ABIN6138817

Produktdetails anti-COASY Antikörper

Target: COASY (CoA Synthase (COASY))

Bindungsspezifität: AA 345-564

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COASY Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: LRPPYERPEL PTCLYVIGLT GISGSGKSSI AQRLKGLGAF VIDSDHLGHR AYAPGGPAYQ PVVEAFGTDI LHKDGIINRK VLGSRVFGNK KQLKILTDIM WPIIAKLARE EMDRAVAEGK RVCVIDAAVL LEAGWQNLVH EVWTAVIPET EAVRRIVERD GLSEAAAQSR LQSQMSGQQL VEQSHVVLST LWEPHITQRQ VEKAWALLQK RIPKTHQALD

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 345-564 of human CoA synthase (COASY) (NP_079509.5).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:100 - 1:200

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu COASY

Target: COASY (CoA Synthase (COASY))

Andere Bezeichnung: COASY (COASY Produkte)

Hintergrund: Coenzyme A (CoA) functions as a carrier of acetyl and acyl groups in cells and thus plays an important role in numerous synthetic and degradative metabolic pathways in all organisms. In eukaryotes, CoA and its derivatives are also involved in membrane trafficking and signal transduction. This gene encodes the bifunctional protein coenzyme A synthase (CoAsy) which carries out the last two steps in the biosynthesis of CoA from pantothenic acid (vitamin B5). The phosphopantetheine adenylyltransferase domain of this bifunctional protein catalyzes the conversion of 4'-phosphopantetheine into dephospho-coenzyme A (dpCoA) while its dephospho-CoA kinase domain completes the final step by phosphorylating dpCoA to form CoA. Mutations in this gene are associated with neurodegeneration with brain iron accumulation (NBIA). Alternative splicing results in multiple isoforms.,COASY,DPCK,NBIA6,NBP,PPAT,UKR1,pOV-2,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,COASY

Molekulargewicht: 62 kDa/65 kDa

Gen-ID: 80347

UniProt: Q13057

Pathways: Ribonucleoside Biosynthetic Process