COX IV Antikörper (AA 23-169)

Produktnummer ABIN6138910

Produktdetails anti-COX IV Antikörper

Target: COX IV (COX4I1) (Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1))

Bindungsspezifität: AA 23-169

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COX IV Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Sequenz: AHESVVKSED FSLPAYMDRR DHPLPEVAHV KHLSASQKAL KEKEKASWSS LSMDEKVELY RIKFKESFAE MNRGSNEWKT VVGGAMFFIG FTALVIMWQK HYVYGPLPQS FDKEWVAKQT KRMLDMKVNP IQGLASKWDY EKNEWKK

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 23-169 of human COX IV (NP_001852.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200,IP,1:50 - 1:100

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-COX IV Antikörper (ABIN6138910)

Han, Cao, Gao, Wang, Chen, Cai, Zhang, Hu, Ma, Gu, Ding: "ZIC1 acts a tumor suppressor in breast cancer by targeting survivin." in: International journal of oncology, Vol. 53, Issue 3, pp. 937-948, (2018) (PubMed).

Hu, Nie, Chen, Xie, Fan, Wang, Long, Yan, Zhong, Yan: "Leucine reduces reactive oxygen species levels via an energy metabolism switch by activation of the mTOR-HIF-1α pathway in porcine intestinal epithelial cells." in: The international journal of biochemistry & cell biology, Vol. 89, pp. 42-56, (2017) (PubMed).

Details zu COX IV

Target: COX IV (COX4I1) (Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1))

Andere Bezeichnung: COX4I1 (COX4I1 Produkte)

Synonyme: COX4 antikoerper, COX4-1 antikoerper, COXIV antikoerper, mg:bb02d03 antikoerper, zgc:110058 antikoerper, GB20012 antikoerper, AL024441 antikoerper, Cox4 antikoerper, Cox4a antikoerper, cox4 antikoerper, cox4i1 antikoerper, coxiv antikoerper, BcDNA:AT07685 antikoerper, CG10396 antikoerper, COX IV antikoerper, CX41 antikoerper, CX42 antikoerper, Dmel\CG10396 antikoerper, IV antikoerper, cytochrome c oxidase subunit 4I1 antikoerper, cytochrome c oxidase subunit IV isoform 1 antikoerper, cytochrome c oxidase subunit 4 isoform 1, mitochondrial antikoerper, cytochrome c oxidase polypeptide IV antikoerper, cytochrome c oxidase subunit IV antikoerper, cytochrome c oxidase subunit 4i1 antikoerper, cytochrome c oxidase subunit IV isoform 1 S homeolog antikoerper, Cytochrome c oxidase subunit 4-like antikoerper, COX4I1 antikoerper, cox4i1 antikoerper, LOC412396 antikoerper, Cox4I1 antikoerper, LOC780848 antikoerper, BMEII0322 antikoerper, RSal33209_1582 antikoerper, SJAG_00976 antikoerper, HMPREF0733_11926 antikoerper, Cox4i1 antikoerper, cox4i1.S antikoerper, COX4L antikoerper

Hintergrund: Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. Pseudogenes related to this gene are located on chromosomes 13 and 14. Alternative splicing results in multiple transcript variants encoding different isoforms.,COX4I1,COX IV-1,COX4,COX4-1,COXIV,COXIV-1,COX IV,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Oxidative phosphorylation,Neuroscience,Neurodegenerative Diseases,COX4I1

Molekulargewicht: 19 kDa

Gen-ID: 1327

UniProt: P13073

Pathways: Proton Transport