Casein Kinase 1 gamma 2 Antikörper (AA 316-415)
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- Target Alle Casein Kinase 1 gamma 2 (CSNK1G2) Antikörper anzeigen
- Casein Kinase 1 gamma 2 (CSNK1G2) (Casein Kinase 1, gamma 2 (CSNK1G2))
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Bindungsspezifität
- AA 316-415
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Casein Kinase 1 gamma 2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- FDRSGFVFDY EYDWAGKPLP TPIGTVHTDL PSQPQLRDKT QPHSKNQALN STNGELNADD PTAGHSNAPI TAPAEVEVAD ETKCCCFFKR RKRKSLQRHK
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
- Polyclonal Antibodies
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 316-415 of human CSNK1G2 (NP_001310.3).
- Isotyp
- IgG
- Top Product
- Discover our top product CSNK1G2 Primärantikörper
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- Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
- Kommentare
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HIGH QUALITY
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- Casein Kinase 1 gamma 2 (CSNK1G2) (Casein Kinase 1, gamma 2 (CSNK1G2))
- Andere Bezeichnung
- CSNK1G2 (CSNK1G2 Produkte)
- Synonyme
- CK1g2 antikoerper, 2810429I12Rik antikoerper, AI463719 antikoerper, CKI antikoerper, ck1-gamma antikoerper, CSNK1G2 antikoerper, ck1g2 antikoerper, csnk1g2 antikoerper, fj97g11 antikoerper, wu:fj97g11 antikoerper, wz8345 antikoerper, zgc:110719 antikoerper, zgc:153415 antikoerper, casein kinase 1 gamma 2 antikoerper, casein kinase 1, gamma 2 antikoerper, casein kinase 1 gamma 2 L homeolog antikoerper, casein kinase 1, gamma 2a antikoerper, casein kinase 1, gamma 2b antikoerper, CSNK1G2 antikoerper, Csnk1g2 antikoerper, csnk1g2.L antikoerper, csnk1g2 antikoerper, csnk1g2a antikoerper, csnk1g2b antikoerper
- Hintergrund
- Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates COL4A3BP/CERT, MTA1 and SMAD3. Involved in brain development and vesicular trafficking and neurotransmitter releasing from small synaptic vesicles. Regulates fast synaptic transmission mediated by glutamate. SMAD3 phosphorylation promotes its ligand-dependent ubiquitination and subsequent proteasome degradation, thus inhibiting SMAD3-mediated TGF-beta responses. Hyperphosphorylation of the serine-repeat motif of COL4A3BP/CERT leads to its inactivation by dissociation from the Golgi complex, thus down-regulating ER-to-Golgi transport of ceramide and sphingomyelin synthesis. Triggers PER1 proteasomal degradation probably through phosphorylation.,CSNK1G2,CK1g2,Cancer,Signal Transduction,Kinase,Endocrine & Metabolism,Lipid Metabolism,Stem Cells,CSNK1G2
- Molekulargewicht
- 47 kDa
- Gen-ID
- 1455
- UniProt
- P78368
- Pathways
- Hedgehog Signalweg
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