Cathepsin L Antikörper (AA 114-333)

Produktnummer ABIN6139235

Produktdetails anti-Cathepsin L Antikörper

Target: Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))

Bindungsspezifität: AA 114-333

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cathepsin L Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Sequenz: APRSVDWREK GYVTPVKNQG QCGSCWAFSA TGALEGQMFR KTGRLISLSE QNLVDCSGPQ GNEGCNGGLM DYAFQYVQDN GGLDSEESYP YEATEESCKY NPKYSVANDT GFVDIPKQEK ALMKAVATVG PISVAIDAGH ESFLFYKEGI YFEPDCSSED MDHGVLVVGY GFESTESDNN KYWLVKNSWG EEWGMGGYVK MAKDRRNHCG IASAASYPTV

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 114-333 of human Cathepsin L/V/K/H (NP_001903.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Cathepsin L

Target: Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))

Andere Bezeichnung: CTSL (CTSL1 Produkte)

Synonyme: CATL antikoerper, CTSL1 antikoerper, MEP antikoerper, 1190035F06Rik antikoerper, Ctsl1 antikoerper, fs antikoerper, nkt antikoerper, CATHL antikoerper, CatL antikoerper, Ctsl antikoerper, CTSL antikoerper, mep antikoerper, catl antikoerper, ctsl antikoerper, cpl-1 antikoerper, MGC80629 antikoerper, MGC107932 antikoerper, LOC663234 antikoerper, 26-29-p antikoerper, Cp1 antikoerper, si:dkey-121a11.6 antikoerper, CTSV antikoerper, catL antikoerper, cb15 antikoerper, ctsl1b antikoerper, hgg1 antikoerper, wu:fb30g09 antikoerper, zgc:92089 antikoerper, cathepsin L antikoerper, cathepsin V antikoerper, cathepsin L L homeolog antikoerper, cathepsin L1 antikoerper, Cathepsin L1 antikoerper, Cathepsin L antikoerper, testin gene antikoerper, cathepsin 12 antikoerper, cathepsin Lb antikoerper, cathepsin L.1 antikoerper, CTSL antikoerper, Ctsl antikoerper, CTSV antikoerper, ctsl.L antikoerper, ctsl antikoerper, LOC100008830 antikoerper, catl1 antikoerper, 26-29-p antikoerper, catl antikoerper, Tsp_11596 antikoerper, Testin antikoerper, cts12 antikoerper, LOC102156614 antikoerper, ctslb antikoerper, ctsl.1 antikoerper

Hintergrund: The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Multiple alternatively spliced transcript variants have been found for this gene.,CTSL,CATL,CTSL1,MEP,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Extracellular Matrix,Neuroscience,CTSL

Molekulargewicht: 37 kDa

Gen-ID: 1514

UniProt: P07711

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades