Cortactin Antikörper (AA 214-513)

Produktnummer ABIN6139243

Produktdetails anti-Cortactin Antikörper

Target: Cortactin (CTTN)

Bindungsspezifität: AA 214-513

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cortactin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: EYQGKTEKHE SQKDYVKGFG GKFGVQTDRQ DKCALGWDHQ EKLQLHESQK DYSKGFGGKY GVQKDRMDKN ASTFEDVTQV SSAYQKTVPV EAVTSKTSNI RANFENLAKE KEQEDRRKAE AERAQRMAKE RQEQEEARRK LEEQARAKTQ TPPVSPAPQP TEERLPSSPV YEDAASFKAE LSYRGPVSGT EPEPVYSMEA ADYREASSQQ GLAYATEAVY ESAEAPGHYP AEDSTYDEYE NDLGITAVAL YDYQAAGDDE ISFDPDDIIT NIEMIDDGWW RGVCKGRYGL FPANYVELRQ

Kreuzreaktivität: Human

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 214-513 of human Cortactin (NP_612632.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Cortactin

Target: Cortactin (CTTN)

Andere Bezeichnung: CTTN (CTTN Produkte)

Synonyme: EMS1 antikoerper, 1110020L01Rik antikoerper, Ems1 antikoerper, Cttnb antikoerper, CG3637 antikoerper, Dmel\CG3637 antikoerper, cortactin antikoerper, cttn antikoerper, CTTN1 antikoerper, P85.25 antikoerper, Cttn antikoerper, ems1 antikoerper, CTTN antikoerper, cortactin antikoerper, CG3637 gene product from transcript CG3637-RD antikoerper, cortactin S homeolog antikoerper, cortactin L homeolog antikoerper, src substrate cortactin antikoerper, Src substrate cortactin antikoerper, CTTN antikoerper, Cttn antikoerper, Cortactin antikoerper, cttn.S antikoerper, cttn.L antikoerper, cttn antikoerper, CpipJ_CPIJ006351 antikoerper, Bm1_57220 antikoerper, LOC100533277 antikoerper

Hintergrund: This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene.,CTTN,EMS1,cortactin,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Cell Adhesion,Cytoskeleton,Microfilaments,Actins,CTTN

Molekulargewicht: 57 kDa/61 kDa/70 kDa

Gen-ID: 2017

UniProt: Q14247

Pathways: MAPK Signalweg