CYBB Antikörper (AA 100-200)
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- Target Alle CYBB Antikörper anzeigen
- CYBB (Cytochrome B-245, beta Polypeptide (CYBB))
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Bindungsspezifität
- AA 100-200
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CYBB Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- FHKMVAWMIA LHSAIHTIAH LFNVEWCVNA RVNNSDPYSV ALSELGDRQN ESYLNFARKR IKNPEGGLYL AVTLLAGITG VVITLCLILI ITSSTKTIRR S
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
- Polyclonal Antibodies
- Aufreinigung
- Affinity purification
- Immunogen
- A synthetic peptide corresponding to a sequence within amino acids 100-200 of human NOX2/gp91phox (NP_000388.2).
- Isotyp
- IgG
- Top Product
- Discover our top product CYBB Primärantikörper
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- Applikationshinweise
- WB,1:500 - 1:2000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- CYBB (Cytochrome B-245, beta Polypeptide (CYBB))
- Andere Bezeichnung
- CYBB (CYBB Produkte)
- Hintergrund
- Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase, neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole.,AMCBX2,CGD,GP91-1,GP91-PHOX,GP91PHOX,IMD34,NOX2,p91-PHOX,CYBB,Cancer,Endocrine & Metabolism,Immunology & Inflammation,CYBB
- Molekulargewicht
- 65 kDa
- Gen-ID
- 1536
- UniProt
- P04839
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