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DBNL Antikörper (AA 131-430)

DBNL Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6139426
  • Target Alle DBNL Antikörper anzeigen
    DBNL (Drebrin-Like (DBNL))
    Bindungsspezifität
    • 15
    • 8
    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 131-430
    Reaktivität
    • 24
    • 19
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 36
    • 2
    • 1
    Kaninchen
    Klonalität
    • 37
    • 2
    Polyklonal
    Konjugat
    • 15
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DBNL Antikörper ist unkonjugiert
    Applikation
    • 37
    • 18
    • 13
    • 13
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    Western Blotting (WB), Immunofluorescence (IF)
    Sequenz
    KVAKASGANY SFHKESGRFQ DVGPQAPVGS VYQKTNAVSE IKRVGKDSFW AKAEKEEENR RLEEKRRAEE AQRQLEQERR ERELREAARR EQRYQEQGGE ASPQRTWEQQ QEVVSRNRNE QESAVHPREI FKQKERAMST TSISSPQPGK LRSPFLQKQL TQPETHFGRE PAAAISRPRA DLPAEEPAPS TPPCLVQAEE EAVYEEPPEQ ETFYEQPPLV QQQGAGSEHI DHHIQGQGLS GQGLCARALY DYQAADDTEI SFDPENLITG IEVIDEGWWR GYGPDGHFGM FPANYVELIE
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 131-430 of human DBNL (NP_001014436.1).
    Isotyp
    IgG
    Top Product
    Discover our top product DBNL Primärantikörper
  • Applikationshinweise
    WB,1:500 - 1:2000,IF,1:50 - 1:100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    DBNL (Drebrin-Like (DBNL))
    Andere Bezeichnung
    DBNL (DBNL Produkte)
    Synonyme
    ABP1 antikoerper, HIP-55 antikoerper, HIP55 antikoerper, SH3P7 antikoerper, Abp1 antikoerper, mAbp1 antikoerper, Sh3p7 antikoerper, abp1 antikoerper, dbnl-B antikoerper, DBNL antikoerper, DKFZp459C0939 antikoerper, drebrin like antikoerper, drebrin-like antikoerper, drebrin like S homeolog antikoerper, drebrin 1 antikoerper, DBNL antikoerper, Dbnl antikoerper, dbnl.S antikoerper, LOC100148204 antikoerper, DBN1 antikoerper
    Hintergrund
    Adapter protein that binds F-actin and DNM1, and thereby plays a role in receptor-mediated endocytosis. Plays a role in the reorganization of the actin cytoskeleton, formation of cell projections, such as neurites, in neuron morphogenesis and synapse formation via its interaction with WASL and COBL. Does not bind G-actin and promote actin polymerization by itself. Required for the formation of organized podosome rosettes (By similarity. May act as a common effector of antigen receptor-signaling pathways in leukocytes. Acts as a key component of the immunological synapse that regulates T-cell activation by bridging TCRs and the actin cytoskeleton to gene activation and endocytic processes.,DBNL,ABP1,HIP-55,HIP55,SH3P7,Signal Transduction,DBNL
    Molekulargewicht
    37 kDa/43 kDa/48 kDa/49 kDa
    Gen-ID
    28988
    UniProt
    Q9UJU6
    Pathways
    T-Zell Rezeptor Signalweg, Regulation of Actin Filament Polymerization
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