Dopamine d2 Receptor Antikörper (AA 214-373)

Produktnummer ABIN6139821

Produktdetails anti-Dopamine d2 Receptor Antikörper

Target: Dopamine d2 Receptor (DRD2) (Dopamine Receptor D2 (DRD2))

Bindungsspezifität: AA 214-373

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Dopamine d2 Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: IVLRRRRKRV NTKRSSRAFR AHLRAPLKGN CTHPEDMKLC TVIMKSNGSF PVNRRRVEAA RRAQELEMEM LSSTSPPERT RYSPIPPSHH QLTLPDPSHH GLHSTPDSPA KPEKNGHAKD HPKIAKIFEI QTMPNGKTRT SLKTMSRRKL SQQKEKKATQ

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 214-373 of human DRD2 (NP_000786.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Dopamine d2 Receptor

Target: Dopamine d2 Receptor (DRD2) (Dopamine Receptor D2 (DRD2))

Andere Bezeichnung: DRD2 (DRD2 Produkte)

Synonyme: D2DR antikoerper, D2R antikoerper, drd2b antikoerper, d2r2 antikoerper, Drd-2 antikoerper, d2dr antikoerper, d2r antikoerper, drd2 antikoerper, drd2-B antikoerper, DRD2 antikoerper, D2 antikoerper, CG18741 antikoerper, CG7569 antikoerper, DAMB antikoerper, DDR2 antikoerper, DOPR2 antikoerper, DOPR99B antikoerper, Dar2 antikoerper, Dmel\\CG18741 antikoerper, DopD1 antikoerper, DopR99B antikoerper, DopRII antikoerper, dopamine receptor D2 antikoerper, dopamine receptor D2 like antikoerper, dopamine receptor D2 L homeolog antikoerper, dopamine receptor D2 S homeolog antikoerper, Dopamine 1-like receptor 2 antikoerper, DRD2 antikoerper, drd2l antikoerper, drd2 antikoerper, Drd2 antikoerper, drd2.L antikoerper, drd2.S antikoerper, Dop1R2 antikoerper

Hintergrund: This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia, other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing.,DRD2,D2DR,D2R,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Neuroscience,Cell Type Marker,Neurodegenerative Diseases,Dopamine Signaling in Parkinson's Disease,Neuron marker,Dendrite marker,DRD2

Molekulargewicht: 47 kDa/50 kDa

Gen-ID: 1813

UniProt: P14416

Pathways: Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Inositol Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity