DYNC2H1 Antikörper (AA 1-250)

Produktnummer ABIN6139887

Produktdetails anti-DYNC2H1 Antikörper

Target: DYNC2H1 (Dynein, Cytoplasmic 2, Heavy Chain 1 (DYNC2H1))

Bindungsspezifität: AA 1-250

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DYNC2H1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MANGTADVRK LFIFTTTQNY FGLMSELWDQ PLLCNCLEIN NFLDDGNQML LRVQRSDAGI SFSNTIEFGD TKDKVLVFFK LRPEVITDEN LHDNILVSSM LESPISSLYQ AVRQVFAPML LKDQEWSRNF DPKLQNLLSE LEAGLGIVLR RSDTNLTKLK FKEDDTRGIL TPSDEFQFWI EQAHRGNKQI SKERANYFKE LFETIAREFY NLDSLSLLEV VDLVETTQDV VDDVWRQTEH DHYPESRMLH

Kreuzreaktivität: Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human DYNC2H1 (NP_001073932.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu DYNC2H1

Target: DYNC2H1 (Dynein, Cytoplasmic 2, Heavy Chain 1 (DYNC2H1))

Andere Bezeichnung: DYNC2H1 (DYNC2H1 Produkte)

Hintergrund: This gene encodes a large cytoplasmic dynein protein that is involved in retrograde transport in the cilium and has a role in intraflagellar transport, a process required for ciliary/flagellar assembly. Mutations in this gene cause a heterogeneous spectrum of conditions related to altered primary cilium function and often involve polydactyly, abnormal skeletogenesis, and polycystic kidneys. Alternative splicing results in multiple transcript variants encoding distinct proteins.,DYNC2H1,ATD3,DHC1b,DHC2,DNCH2,DYH1B,SRPS2B,SRTD3,hdhc11,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Centromere,Cytoskeleton,Motor Proteins,DYNC2H1

Molekulargewicht: 105 kDa/492 kDa/493 kDa

Gen-ID: 79659

UniProt: Q8NCM8

Pathways: Hedgehog Signalweg, Asymmetric Protein Localization