ERO1LB Antikörper (AA 34-230)

Produktnummer ABIN6140294

Produktdetails anti-ERO1LB Antikörper

Target: ERO1LB (ERO1-Like beta (ERO1LB))

Bindungsspezifität: AA 34-230

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ERO1LB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: QVTGVLDDCL CDIDSIDNFN TYKIFPKIKK LQERDYFRYY KVNLKRPCPF WAEDGHCSIK DCHVEPCPES KIPVGIKAGH SNKYLKMANN TKELEDCEQA NKLGAINSTL SNQSKEAFID WARYDDSRDH FCELDDERSP AAQYVDLLLN PERYTGYKGT SAWRVWNSIY EENCFKPRSV YRPLNPLAPS RGEDDGE

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 34-230 of human ERO1LB (NP_063944.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ERO1LB

Target: ERO1LB (ERO1-Like beta (ERO1LB))

Andere Bezeichnung: ERO1LB (ERO1LB Produkte)

Synonyme: RGD1563548 antikoerper, 1300013B24Rik antikoerper, 1700065B09Rik antikoerper, AI447560 antikoerper, ero1-beta antikoerper, endoplasmic reticulum oxidoreductase 1 beta antikoerper, ERO1-like beta (S. cerevisiae) antikoerper, Ero1b antikoerper, ERO1B antikoerper, Ero1lb antikoerper

Hintergrund: Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Other protein disulfide isomerase family members can also be reoxidized, but at lower rates compared to P4HB, including PDIA2 (50 % of P4HB reoxidation rate, as well as PDIA3, PDIA4, PDIA6 and NXNDC12 (<10 %. Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS in the cell. May be involved in oxidative proinsulin folding in pancreatic cells, hence may play a role in glucose homeostasis.,ERO1B,ERO1LB,Ero1beta,Signal Transduction,ERO1LB

Molekulargewicht: 16 kDa/53 kDa

Gen-ID: 56605

UniProt: Q86YB8

Pathways: SARS-CoV-2 Protein Interaktom