ETV1 Antikörper (AA 80-300)

Produktnummer ABIN6140327

Produktdetails anti-ETV1 Antikörper

Target: ETV1 (Ets Variant 1 (ETV1))

Bindungsspezifität: AA 80-300

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ETV1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequenz: AFHGLPLKIK KEPHSPCSEI SSACSQEQPF KFSYGEKCLY NVSAYDQKPQ VGMRPSNPPT PSSTPVSPLH HASPNSTHTP KPDRAFPAHL PPSQSIPDSS YPMDHRFRRQ LSEPCNSFPP LPTMPREGRP MYQRQMSEPN IPFPPQGFKQ EYHDPVYEHN TMVGSAASQS FPPPLMIKQE PRDFAYDSEV PSCHSIYMRQ EGFLAHPSRT EGCMFEKGPR Q

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 80-300 of human ETV1 (NP_004947.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC,1:50 - 1:200,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ETV1

Target: ETV1 (Ets Variant 1 (ETV1))

Andere Bezeichnung: ETV1 (ETV1 Produkte)

Synonyme: er81 antikoerper, XER81 antikoerper, MGC75591 antikoerper, ER81 antikoerper, Etsrp81 antikoerper, ETS variant 1 antikoerper, ets variant 1 antikoerper, ETS variant 1 S homeolog antikoerper, etv1 antikoerper, ETV1 antikoerper, Etv1 antikoerper, etv1.S antikoerper

Hintergrund: This gene encodes a member of the ETS (E twenty-six) family of transcription factors. The ETS proteins regulate many target genes that modulate biological processes like cell growth, angiogenesis, migration, proliferation and differentiation. All ETS proteins contain an ETS DNA-binding domain that binds to DNA sequences containing the consensus 5'-CGGA[AT]-3'. The protein encoded by this gene contains a conserved short acidic transactivation domain (TAD) in the N-terminal region, in addition to the ETS DNA-binding domain in the C-terminal region. This gene is involved in chromosomal translocations, which result in multiple fusion proteins including EWS-ETV1 in Ewing sarcoma and at least 10 ETV1 partners (see PMID: 19657377, Table 1) in prostate cancer. In addition to chromosomal rearrangement, this gene is overexpressed in prostate cancer, melanoma and gastrointestinal stromal tumor. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.,ETV1,ER81,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,MAPK-Erk Signaling Pathway,MAPK-P38 Signaling Pathway,Neuroscience,Stem Cells,Hematopoietic Progenitors,ETV1

Molekulargewicht: 43 kDa/48 kDa/50 kDa/52 kDa/53 kDa/55 kDa

Gen-ID: 2115

UniProt: P50549