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FAM3B Antikörper (AA 30-235)

FAM3B Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6140457
  • Target Alle FAM3B Antikörper anzeigen
    FAM3B (Family with Sequence Similarity 3, Member B (FAM3B))
    Bindungsspezifität
    • 15
    • 8
    • 7
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 30-235
    Reaktivität
    • 40
    • 22
    • 19
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 51
    • 5
    Kaninchen
    Klonalität
    • 53
    • 3
    Polyklonal
    Konjugat
    • 23
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FAM3B Antikörper ist unkonjugiert
    Applikation
    • 43
    • 23
    • 13
    • 13
    • 12
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    ELIPDAPLSS AAYSIRSIGE RPVLKAPVPK RQKCDHWTPC PSDTYAYRLL SGGGRSKYAK ICFEDNLLMG EQLGNVARGI NIAIVNYVTG NVTATRCFDM YEGDNSGPMT KFIQSAAPKS LLFMVTYDDG STRLNNDAKN AIEALGSKEI RNMKFRSSWV FIAAKGLELP SEIQREKINH SDAKNNRYSG WPAEIQIEGC IPKERS
    Kreuzreaktivität
    Human, Maus
    Produktmerkmale
    Polyclonal Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 30-235 of human FAM3B (NP_478066.3).
    Isotyp
    IgG
    Top Product
    Discover our top product FAM3B Primärantikörper
  • Applikationshinweise
    WB,1:500 - 1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    FAM3B (Family with Sequence Similarity 3, Member B (FAM3B))
    Andere Bezeichnung
    FAM3B (FAM3B Produkte)
    Synonyme
    2-21 antikoerper, C21orf11 antikoerper, C21orf76 antikoerper, ORF9 antikoerper, PANDER antikoerper, 9030624C24Rik antikoerper, D16Jhu19e antikoerper, Pander antikoerper, RGD1311662 antikoerper, family with sequence similarity 3 member B antikoerper, family with sequence similarity 3, member B antikoerper, FAM3B antikoerper, Fam3b antikoerper
    Substanzklasse
    Viral Protein
    Hintergrund
    FAM3B, also known as Pancreatic-derived factor (PANDER), is an islet-specific secreted cytokine specifically expressed at high levels in the islets of Langerhans of the endocrine pancreas. FAM3B can induce apoptosis of alpha and beta cells in a dose- and time-dependent manner. Previous studies showed that FAM3B regulates glucose and lipid metabolism through interaction with liver and endocrine pancreas. FAM3B silencing activates both extrinsic and intrinsic apoptotic pathways. In general, silencing FAM3B promoted p53 phosphorylation and induced p53 accumulation by decreasing Mdm2 expression, which resulted in apoptotic cell death.,FAM3B,2-21,C21orf11,C21orf76,ORF9,PANDER,PRED44,Endocrine & Metabolism,Endocrine and metabolic diseases,Diabetes,Metabolic disorders,Obesity,Immunology & Inflammation,Cytokines,Cell Intrinsic Innate Immunity Signaling Pathway,FAM3B
    Molekulargewicht
    20 kDa/25 kDa/30 kDa
    Gen-ID
    54097
    UniProt
    P58499
    Pathways
    Hormone Transport
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