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FERMT2 Antikörper (AA 380-550)

FERMT2 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6140582
  • Target Alle FERMT2 Antikörper anzeigen
    FERMT2 (Fermitin Family Member 2 (FERMT2))
    Bindungsspezifität
    • 15
    • 14
    • 9
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 380-550
    Reaktivität
    • 49
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 39
    • 10
    Kaninchen
    Klonalität
    • 39
    • 10
    Polyklonal
    Konjugat
    • 21
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FERMT2 Antikörper ist unkonjugiert
    Applikation
    • 44
    • 22
    • 13
    • 13
    • 7
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    KVFKPKKLTL KGYKQYWCTF KDTSISCYKS KEESSGTPAH QMNLRGCEVT PDVNISGQKF NIKLLIPVAE GMNEIWLRCD NEKQYAHWMA ACRLASKGKT MADSSYNLEV QNILSFLKMQ HLNPDPQLIP EQITTDITPE CLVSPRYLKK YKNKQITARI LEAHQNVAQM S
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 380-550 of human FERMT2 (NP_006823.1).
    Isotyp
    IgG
    Top Product
    Discover our top product FERMT2 Primärantikörper
  • Applikationshinweise
    WB,1:1000 - 1:2000,IHC,1:50 - 1:200
    Kommentare

    HIGH QUALITY

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    FERMT2 (Fermitin Family Member 2 (FERMT2))
    Andere Bezeichnung
    FERMT2 (FERMT2 Produkte)
    Synonyme
    AA960555 antikoerper, Kindlin-2 antikoerper, Mig2 antikoerper, Plekhc1 antikoerper, KIND2 antikoerper, MIG2 antikoerper, PLEKHC1 antikoerper, UNC112 antikoerper, UNC112B antikoerper, mig-2 antikoerper, fermitin family member 2 antikoerper, Fermt2 antikoerper, FERMT2 antikoerper
    Hintergrund
    Scaffolding protein that enhances integrin activation mediated by TLN1 and/or TLN2, but activates integrins only weakly by itself. Binds to membranes enriched in phosphoinositides. Enhances integrin-mediated cell adhesion onto the extracellular matrix and cell spreading, this requires both its ability to interact with integrins and with phospholipid membranes. Required for the assembly of focal adhesions. Participates in the connection between extracellular matrix adhesion sites and the actin cytoskeleton and also in the orchestration of actin assembly and cell shape modulation. Recruits FBLIM1 to focal adhesions. Plays a role in the TGFB1 and integrin signaling pathways. Stabilizes active CTNNB1 and plays a role in the regulation of transcription mediated by CTNNB1 and TCF7L2/TCF4 and in Wnt signaling.,FERMT2,KIND2,MIG2,PLEKHC1,UNC112,UNC112B,mig-2,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Stem Cells,Mesenchymal Stem Cells,FERMT2
    Molekulargewicht
    72 kDa/77 kDa/78 kDa
    Gen-ID
    10979
    UniProt
    Q96AC1
    Pathways
    Cell-Cell Junction Organization
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