FERMT2 Antikörper (AA 380-550)
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- Target Alle FERMT2 Antikörper anzeigen
- FERMT2 (Fermitin Family Member 2 (FERMT2))
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Bindungsspezifität
- AA 380-550
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser FERMT2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- KVFKPKKLTL KGYKQYWCTF KDTSISCYKS KEESSGTPAH QMNLRGCEVT PDVNISGQKF NIKLLIPVAE GMNEIWLRCD NEKQYAHWMA ACRLASKGKT MADSSYNLEV QNILSFLKMQ HLNPDPQLIP EQITTDITPE CLVSPRYLKK YKNKQITARI LEAHQNVAQM S
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
- Polyclonal Antibodies
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 380-550 of human FERMT2 (NP_006823.1).
- Isotyp
- IgG
- Top Product
- Discover our top product FERMT2 Primärantikörper
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- Applikationshinweise
- WB,1:1000 - 1:2000,IHC,1:50 - 1:200
- Kommentare
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HIGH QUALITY
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- FERMT2 (Fermitin Family Member 2 (FERMT2))
- Andere Bezeichnung
- FERMT2 (FERMT2 Produkte)
- Synonyme
- AA960555 antikoerper, Kindlin-2 antikoerper, Mig2 antikoerper, Plekhc1 antikoerper, KIND2 antikoerper, MIG2 antikoerper, PLEKHC1 antikoerper, UNC112 antikoerper, UNC112B antikoerper, mig-2 antikoerper, fermitin family member 2 antikoerper, Fermt2 antikoerper, FERMT2 antikoerper
- Hintergrund
- Scaffolding protein that enhances integrin activation mediated by TLN1 and/or TLN2, but activates integrins only weakly by itself. Binds to membranes enriched in phosphoinositides. Enhances integrin-mediated cell adhesion onto the extracellular matrix and cell spreading, this requires both its ability to interact with integrins and with phospholipid membranes. Required for the assembly of focal adhesions. Participates in the connection between extracellular matrix adhesion sites and the actin cytoskeleton and also in the orchestration of actin assembly and cell shape modulation. Recruits FBLIM1 to focal adhesions. Plays a role in the TGFB1 and integrin signaling pathways. Stabilizes active CTNNB1 and plays a role in the regulation of transcription mediated by CTNNB1 and TCF7L2/TCF4 and in Wnt signaling.,FERMT2,KIND2,MIG2,PLEKHC1,UNC112,UNC112B,mig-2,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Stem Cells,Mesenchymal Stem Cells,FERMT2
- Molekulargewicht
- 72 kDa/77 kDa/78 kDa
- Gen-ID
- 10979
- UniProt
- Q96AC1
- Pathways
- Cell-Cell Junction Organization
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