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FGD4 Antikörper (AA 99-198)

FGD4 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6140588
  • Target Alle FGD4 Antikörper anzeigen
    FGD4 (FYVE, RhoGEF and PH Domain Containing 4 (FGD4))
    Bindungsspezifität
    • 8
    • 8
    • 7
    • 2
    • 1
    AA 99-198
    Reaktivität
    • 22
    • 1
    • 1
    Human
    Wirt
    • 22
    Kaninchen
    Klonalität
    • 22
    Polyklonal
    Konjugat
    • 12
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser FGD4 Antikörper ist unkonjugiert
    Applikation
    • 21
    • 13
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    QMECEEEKAA TLSSDTSIQA SEPLLDTHIV NGERDETATA PASPTTDSCD GNASDSSYRT PGIGPVLPLE ERGAETETKV QERENGESPL ELEQLDQHHE
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 99-198 of human FGD4 (NP_640334.2).
    Isotyp
    IgG
    Top Product
    Discover our top product FGD4 Primärantikörper
  • Applikationshinweise
    WB,1:500 - 1:2000
    Kommentare

    HIGH QUALITY

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    FGD4 (FYVE, RhoGEF and PH Domain Containing 4 (FGD4))
    Andere Bezeichnung
    FGD4 (FGD4 Produkte)
    Synonyme
    CMT4H antikoerper, FRABP antikoerper, ZFYVE6 antikoerper, 9030023J02Rik antikoerper, 9330209B17Rik antikoerper, Frabp antikoerper, FYVE, RhoGEF and PH domain containing 4 antikoerper, FGD4 antikoerper, Fgd4 antikoerper
    Hintergrund
    This gene encodes a protein that is involved in the regulation of the actin cytoskeleton and cell shape. This protein contains an actin filament-binding domain, which together with its Dbl homology domain and one of its pleckstrin homology domains, can form microspikes. This protein can activate MAPK8 independently of the actin filament-binding domain, and it is also involved in the activation of CDC42 via the exchange of bound GDP for free GTP. The activation of CDC42 also enables this protein to play a role in mediating the cellular invasion of Cryptosporidium parvum, an intracellular parasite that infects the gastrointestinal tract. Mutations in this gene can cause Charcot-Marie-Tooth disease type 4H (CMT4H), a disorder of the peripheral nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.,FGD4,CMT4H,FRABP,ZFYVE6,FYVE,FGD4
    Molekulargewicht
    20 kDa/32 kDa/86 kDa
    Gen-ID
    121512
    UniProt
    Q96M96
    Pathways
    Neurotrophin Signalübertragung
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