FGD4 Antikörper (AA 99-198)
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- Target Alle FGD4 Antikörper anzeigen
- FGD4 (FYVE, RhoGEF and PH Domain Containing 4 (FGD4))
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Bindungsspezifität
- AA 99-198
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser FGD4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- QMECEEEKAA TLSSDTSIQA SEPLLDTHIV NGERDETATA PASPTTDSCD GNASDSSYRT PGIGPVLPLE ERGAETETKV QERENGESPL ELEQLDQHHE
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
- Polyclonal Antibodies
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 99-198 of human FGD4 (NP_640334.2).
- Isotyp
- IgG
- Top Product
- Discover our top product FGD4 Primärantikörper
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- Applikationshinweise
- WB,1:500 - 1:2000
- Kommentare
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HIGH QUALITY
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- FGD4 (FYVE, RhoGEF and PH Domain Containing 4 (FGD4))
- Andere Bezeichnung
- FGD4 (FGD4 Produkte)
- Synonyme
- CMT4H antikoerper, FRABP antikoerper, ZFYVE6 antikoerper, 9030023J02Rik antikoerper, 9330209B17Rik antikoerper, Frabp antikoerper, FYVE, RhoGEF and PH domain containing 4 antikoerper, FGD4 antikoerper, Fgd4 antikoerper
- Hintergrund
- This gene encodes a protein that is involved in the regulation of the actin cytoskeleton and cell shape. This protein contains an actin filament-binding domain, which together with its Dbl homology domain and one of its pleckstrin homology domains, can form microspikes. This protein can activate MAPK8 independently of the actin filament-binding domain, and it is also involved in the activation of CDC42 via the exchange of bound GDP for free GTP. The activation of CDC42 also enables this protein to play a role in mediating the cellular invasion of Cryptosporidium parvum, an intracellular parasite that infects the gastrointestinal tract. Mutations in this gene can cause Charcot-Marie-Tooth disease type 4H (CMT4H), a disorder of the peripheral nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.,FGD4,CMT4H,FRABP,ZFYVE6,FYVE,FGD4
- Molekulargewicht
- 20 kDa/32 kDa/86 kDa
- Gen-ID
- 121512
- UniProt
- Q96M96
- Pathways
- Neurotrophin Signalübertragung
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