Filamin A Antikörper (AA 2348-2647)

Produktnummer ABIN6140677

Produktdetails anti-Filamin A Antikörper

Target: Filamin A (FLNA) (Filamin A, alpha (FLNA))

Bindungsspezifität: AA 2348-2647

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Filamin A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Sequenz: NQPASFAVSL NGAKGAIDAK VHSPSGALEE CYVTEIDQDK YAVRFIPREN GVYLIDVKFN GTHIPGSPFK IRVGEPGHGG DPGLVSAYGA GLEGGVTGNP AEFVVNTSNA GAGALSVTID GPSKVKMDCQ ECPEGYRVTY TPMAPGSYLI SIKYGGPYHI GGSPFKAKVT GPRLVSNHSL HETSSVFVDS LTKATCAPQH GAPGPGPADA SKVVAKGLGL SKAYVGQKSS FTVDCSKAGN NMLLVGVHGP RTPCEEILVK HVGSRLYSVS YLLKDKGEYT LVVKWGDEHI PGSPYRVVVP

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 2348-2647 of human Filamin A (NP_001104026.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IP,1:50 - 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Filamin A

Target: Filamin A (FLNA) (Filamin A, alpha (FLNA))

Andere Bezeichnung: FLNA (FLNA Produkte)

Synonyme: ABP-280 antikoerper, ABPX antikoerper, CSBS antikoerper, CVD1 antikoerper, FLN antikoerper, FLN-A antikoerper, FLN1 antikoerper, FMD antikoerper, MNS antikoerper, NHBP antikoerper, OPD antikoerper, OPD1 antikoerper, OPD2 antikoerper, XLVD antikoerper, XMVD antikoerper, fb98b06 antikoerper, wu:fb98b06 antikoerper, wu:fd09g03 antikoerper, wu:fd49a06 antikoerper, Dilp2 antikoerper, F730004A14Rik antikoerper, Fln1 antikoerper, filamin-1 antikoerper, RGD1560614 antikoerper, MGC147094 antikoerper, CG3937 antikoerper, Cher antikoerper, Dmel\\CG3937 antikoerper, Fil antikoerper, joy antikoerper, sko antikoerper, filamin A antikoerper, filamin A, alpha (actin binding protein 280) antikoerper, filamin, alpha antikoerper, filamin-A antikoerper, cheerio antikoerper, FLNA antikoerper, flna antikoerper, Flna antikoerper, LOC587317 antikoerper, cher antikoerper, LOC100380643 antikoerper

Hintergrund: The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.,FLNA,ABP-280,ABPX,CSBS,CVD1,FLN,FLN-A,FLN1,FMD,MNS,NHBP,OPD,OPD1,OPD2,XLVD,XMVD,filamin-A,Epigenetics & Nuclear Signaling,RNA Binding,Signal Transduction,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,Actins,FLNA

Molekulargewicht: 280 kDa

Gen-ID: 2316

UniProt: P21333

Pathways: T-Zell Rezeptor Signalweg, Maintenance of Protein Location