FLT3 Antikörper (AA 650-750)
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- Target Alle FLT3 Antikörper anzeigen
- FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))
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Bindungsspezifität
- AA 650-750
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser FLT3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- ADSSEREALM SELKMMTQLG SHENIVNLLG ACTLSGPIYL IFEYCCYGDL LNYLRSKREK FHRTWTEIFK EHNFSFYPTF QSHPNSSMPG SREVQIHPDS D
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
- Polyclonal Antibodies
- Aufreinigung
- Affinity purification
- Immunogen
- A synthetic peptide corresponding to a sequence within amino acids 650-750 of human FLT3 (NP_004110.2).
- Isotyp
- IgG
- Top Product
- Discover our top product FLT3 Primärantikörper
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- Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
- Kommentare
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HIGH QUALITY
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))
- Andere Bezeichnung
- FLT3 (FLT3 Produkte)
- Synonyme
- FLT3 antikoerper, B230315G04 antikoerper, CD135 antikoerper, Flk-2 antikoerper, Flk2 antikoerper, Flt-3 antikoerper, Ly72 antikoerper, wmfl antikoerper, FLK-2 antikoerper, FLK2 antikoerper, STK1 antikoerper, fms related tyrosine kinase 3 antikoerper, FMS-like tyrosine kinase 3 antikoerper, fms-related tyrosine kinase 3 antikoerper, FLT3 antikoerper, Flt3 antikoerper
- Hintergrund
- This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia.,FLT3,CD135,FLK-2,FLK2,STK1,Signal Transduction,Kinase,Tyrosine kinases,Immunology & Inflammation,CD markers,Stem Cells,FLT3
- Molekulargewicht
- 108 kDa/112 kDa
- Gen-ID
- 2322
- UniProt
- P36888
- Pathways
- RTK Signalweg
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