FOXP2 Antikörper (AA 441-740)

Produktnummer ABIN6140762

Produktdetails anti-FOXP2 Antikörper

Target: FOXP2 (Forkhead Box P2 (FOXP2))

Bindungsspezifität: AA 441-740

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FOXP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: PKPSPKPLNL VSSVTMSKNM LETSPQSLPQ TPTTPTAPVT PITQGPSVIT PASVPNVGAI RRRHSDKYNI PMSSEIAPNY EFYKNADVRP PFTYATLIRQ AIMESSDRQL TLNEIYSWFT RTFAYFRRNA ATWKNAVRHN LSLHKCFVRV ENVKGAVWTV DEVEYQKRRS QKITGSPTLV KNIPTSLGYG AALNASLQAA LAESSLPLLS NPGLINNASS GLLQAVHEDL NGSLDHIDSN GNSSPGCSPQ PHIHSIHVKE EPVIAEDEDC PMSLVTTANH SPELEDDREI EEEPLSEDLE

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 441-740 of human FOXP2 (NP_683696.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu FOXP2

Target: FOXP2 (Forkhead Box P2 (FOXP2))

Andere Bezeichnung: FOXP2 (FOXP2 Produkte)

Hintergrund: This gene encodes a member of the forkhead/winged-helix (FOX) family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal dominant speech and language disorder with orofacial dyspraxia. Multiple alternative transcripts encoding different isoforms have been identified in this gene.,FOXP2,CAGH44,SPCH1,TNRC10,Epigenetics & Nuclear Signaling,Transcription Factors,FOXP2

Molekulargewicht: 9-18 kDa/40- 48 kDa/70- 82 kDa

Gen-ID: 93986

UniProt: O15409