GCSH Antikörper (AA 1-173)

Produktnummer ABIN6141032

Produktdetails anti-GCSH Antikörper

Target: GCSH (Glycine Cleavage System H Protein (GCSH))

Bindungsspezifität: AA 1-173

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GCSH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Sequenz: MALRVVRSVR ALLCTLRAVP SPAAPCPPRP WQLGVGAVRT LRTGPALLSV RKFTEKHEWV TTENGIGTVG ISNFAQEALG DVVYCSLPEV GTKLNKQDEF GALESVKAAS ELYSPLSGEV TEINEALAEN PGLVNKSCYE DGWLIKMTLS NPSELDELMS EEAYEKYIKS IEE

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-173 of human GCSH (NP_004474.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu GCSH

Target: GCSH (Glycine Cleavage System H Protein (GCSH))

Andere Bezeichnung: GCSH (GCSH Produkte)

Synonyme: GCE antikoerper, NKH antikoerper, GCSH antikoerper, H-PROTEIN antikoerper, 1100001L02Rik antikoerper, 5730591C18Rik antikoerper, wu:fb14d10 antikoerper, wu:fw84b08 antikoerper, zgc:112535 antikoerper, BA5228 antikoerper, gce antikoerper, gcsh antikoerper, nkh antikoerper, wu:fd56h06 antikoerper, zgc:110557 antikoerper, zgc:92732 antikoerper, glycine cleavage system protein H antikoerper, glycine cleavage system protein H (aminomethyl carrier) antikoerper, glycine cleavage system lipoyl carrier protein GcvH antikoerper, glycine cleavage system H protein antikoerper, glycine cleavage system protein H (aminomethyl carrier), a antikoerper, glycine cleavage system carrier of aminomethyl moiety GcvH antikoerper, leucine rich repeat containing 34 antikoerper, glycine cleavage system protein H (aminomethyl carrier) L homeolog antikoerper, glycine cleavage system protein H (aminomethyl carrier), b antikoerper, GCSH antikoerper, Gcsh antikoerper, gcvH-2 antikoerper, gcvH antikoerper, gcsha antikoerper, LRRC34 antikoerper, gcsh.L antikoerper, gcshb antikoerper

Hintergrund: Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the H protein, which transfers the methylamine group of glycine from the P protein to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH). Two transcript variants, one protein-coding and the other probably not protein-coding,have been found for this gene. Also, several transcribed and non-transcribed pseudogenes of this gene exist throughout the genome.,GCSH,GCE,NKH,Cancer,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,GCSH

Molekulargewicht: 18 kDa

Gen-ID: 2653

UniProt: P23434