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Connexin 43/GJA1 Antikörper (AA 233-382)

Name: Connexin 43/GJA1 Antikörper (AA 233-382)
Brand: antibodies-online
SKU: ABIN6141098
Price: 722.37 EUR
Availability: InStock

GJA1 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

Western blot analysis of extracts of various cell lines, using Connexin 43 antibody (ABIN6131701, ABIN6141098, ABIN6141099 and ABIN6215448) at 1:1000 dilution. (Connexin 43/GJA1 Antikörper (AA 233-382))

Immunohistochemistry of paraffin-embedded Mouse heart using Connexin 43 Rabbit pAb (ABIN6131701, ABIN6141098, ABIN6141099 and ABIN6215448) at dilution of 1:100 (40x lens). (Connexin 43/GJA1 Antikörper (AA 233-382))

IHC

Immunohistochemistry of paraffin-embedded Rat heart using Connexin 43 Rabbit pAb (ABIN6131701, ABIN6141098, ABIN6141099 and ABIN6215448) at dilution of 1:100 (40x lens). (Connexin 43/GJA1 Antikörper (AA 233-382))

IHC

Immunofluorescence analysis of L929 cells using Connexin 43 Rabbit pAb (ABIN6131701, ABIN6141098, ABIN6141099 and ABIN6215448) at dilution of 1:100 (40x lens). (Connexin 43/GJA1 Antikörper (AA 233-382))

4 Abbildungen

Produktnummer ABIN6141098

Datenblatt (PDF)

Target Alle Connexin 43/GJA1 (GJA1) Antikörper anzeigen

Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))
Bindungsspezifität
20

16

11

8

8

7

7

7

7

4

4

3

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 233-382
Reaktivität
125

89

84

32

11

10

10

8

7

6

6

4

4

3

2

2

2

1

1

1

1

1

1

1

1
Human
Wirt
123

7

3

1
Kaninchen
Passende Sekundärantikörper
Klonalität
126

7
Polyklonal
Konjugat
78

6

4

4

4

4

4

4

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
Dieser Connexin 43/GJA1 Antikörper ist unkonjugiert
Applikation
92

51

46

22

20

16

13

13

10

10

7

5

2

2

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequenz

FKGVKDRVKG KSDPYHATSG ALSPAKDCGS QKYAYFNGCS SPTAPLSPMS PPGYKLVTGD RNNSSCRNYN KQASEQNWAN YSAEQNRMGQ AGSTISNSHA QPFDFPDDNQ NSKKLAAGHE LQPLAIVDQR PSSRASSRAS SRPRPDDLEI

Kreuzreaktivität

Human, Maus, Ratte

Produktmerkmale

Polyclonal Antibodies

Aufreinigung

Affinity purification

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 233-382 of human GJA1 (NP_000156.1).

Isotyp

IgG

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anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (C-Term) antibody
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anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (AA 233-382) antibody
GJA1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated

anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (N-Term) antibody
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anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (AA 331-345), (C-Term), (Intracellular) antibody
GJA1 Reaktivität: Human, Ratte, Maus WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Kommentare

HIGH QUALITY

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

-20 °C

Informationen zur Lagerung

Store at -20°C. Avoid freeze / thaw cycles.
Target

Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))

Andere Bezeichnung

GJA1 (GJA1 Produkte)

Hintergrund

This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. A related intronless pseudogene has been mapped to chromosome 5. Mutations in this gene have been associated with oculodentodigital dysplasia, autosomal recessive craniometaphyseal dysplasia and heart malformations.,GJA1,AVSD3,CMDR,CX43,EKVP,GJAL,HLHS1,HSS,ODDD,PPKCA,EKVP3,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Gap Junctions,Cytoskeleton,Immunology & Inflammation,Cardiovascular,Heart,Cardiac arrhythmias,GJA1

Molekulargewicht

43 kDa

Gen-ID

2697

UniProt

P17302

Pathways

MAPK Signalweg, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization