GLE1 Antikörper (AA 1-300)

Produktnummer ABIN6141121

Produktdetails anti-GLE1 Antikörper

Target: GLE1 (GLE1 RNA Export Mediator (GLE1))

Bindungsspezifität: AA 1-300

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GLE1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MPSEGRCWET LKALRSSDKG RLCYYRDWLL RREDVLEECM SLPKLSSYSG WVVEHVLPHM QENQPLSETS PSSTSASALD QPSFVPKSPD ASSAFSPASP ATPNGTKGKD ESQHTESMVL QSSRGIKVEG CVRMYELVHR MKGTEGLRLW QEEQERKVQA LSEMASEQLK RFDEWKELKQ HKEFQDLREV MEKSSREALG HQEKLKAEHR HRAKILNLKL REAEQQRVKQ AEQERLRKEE GQIRLRALYA LQEEMLQLSQ QLDASEQHKA LLKVDLAAFQ TRGNQLCSLI SGIIRASSES

Kreuzreaktivität: Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human GLE1 (NP_001003722.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:1000 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu GLE1

Target: GLE1 (GLE1 RNA Export Mediator (GLE1))

Andere Bezeichnung: GLE1 (GLE1 Produkte)

Synonyme: Dmel\\CG14749 antikoerper, GLE1 antikoerper, GLE1L antikoerper, LCCS antikoerper, LCCS1 antikoerper, hGLE1 antikoerper, Gle1l antikoerper, 4933405K21Rik antikoerper, AA553313 antikoerper, CG14749 gene product from transcript CG14749-RA antikoerper, nucleoporin GLE1 antikoerper, RNA export factor Gle1 antikoerper, GLE1, RNA export mediator antikoerper, GLE1 RNA export mediator antikoerper, GLE1 RNA export mediator (yeast) antikoerper, CG14749 antikoerper, CpipJ_CPIJ014147 antikoerper, SJAG_03847 antikoerper, GLE1 antikoerper, Gle1 antikoerper

Hintergrund: This gene encodes a predicted 75- kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly(A)+RNA export. Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly(A)+RNA export. Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes. This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.,GLE1,GLE1L,LCCS,LCCS1,hGLE1,Epigenetics & Nuclear Signaling,Signal Transduction,GLE1

Molekulargewicht: 75 kDa/79 kDa

Gen-ID: 2733

UniProt: Q53GS7