GLI1 Antikörper
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- Target Alle GLI1 Antikörper anzeigen
- GLI1 (Zinc Finger Protein GLI1 (GLI1))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GLI1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
- Polyclonal Antibodies
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant protein of human GLI1
- Isotyp
- IgG
- Top Product
- Discover our top product GLI1 Primärantikörper
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- Applikationshinweise
- WB,1:500 - 1:2000
- Kommentare
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HIGH QUALITY
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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Disulfiram/copper targets stem cell-like ALDH+ population of multiple myeloma by inhibition of ALDH1A1 and Hedgehog pathway." in: Journal of cellular biochemistry, Vol. 119, Issue 8, pp. 6882-6893, (2018) (PubMed).
: "Exendin-4 promotes the osteogenic differentiation of osteoblasts via the Hedgehog/Gli1 signaling pathway." in: American journal of translational research, Vol. 10, Issue 1, pp. 315-324, (2018) (PubMed).
: "Arsenic trioxide inhibits cancer stem-like cells via down-regulation of Gli1 in lung cancer." in: American journal of translational research, Vol. 8, Issue 2, pp. 1133-43, (2016) (PubMed).
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Disulfiram/copper targets stem cell-like ALDH+ population of multiple myeloma by inhibition of ALDH1A1 and Hedgehog pathway." in: Journal of cellular biochemistry, Vol. 119, Issue 8, pp. 6882-6893, (2018) (PubMed).
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- Target
- GLI1 (Zinc Finger Protein GLI1 (GLI1))
- Andere Bezeichnung
- GLI1 (GLI1 Produkte)
- Synonyme
- GLI antikoerper, Gli antikoerper, Gli-1 antikoerper, gli1.1 antikoerper, AV235269 antikoerper, Zfp-5 antikoerper, Zfp5 antikoerper, GLI family zinc finger 1 antikoerper, GLI family zinc finger 1 S homeolog antikoerper, GLI-Kruppel family member GLI1 antikoerper, GLI1 antikoerper, Gli1 antikoerper, gli1.S antikoerper, gli1 antikoerper
- Hintergrund
- This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene.,GLI1,GLI,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Tumor suppressors,Signal Transduction,Cell Biology & Developmental Biology,Hedgehog Signaling Pathway,Neuroscience,Stem Cells,GLI1
- Molekulargewicht
- 104 kDa/113 kDa/117 kDa
- Gen-ID
- 2735
- UniProt
- P08151
- Pathways
- Hedgehog Signalweg, Dopaminergic Neurogenesis
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