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GLP1R Antikörper (AA 22-116)

GLP1R Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6141138
  • Target Alle GLP1R Antikörper anzeigen
    GLP1R (Glucagon-Like Peptide 1 Receptor (GLP1R))
    Bindungsspezifität
    • 16
    • 9
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 22-116
    Reaktivität
    • 51
    • 46
    • 30
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 56
    • 2
    • 2
    • 1
    Kaninchen
    Klonalität
    • 59
    • 2
    Polyklonal
    Konjugat
    • 26
    • 6
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GLP1R Antikörper ist unkonjugiert
    Applikation
    • 39
    • 19
    • 19
    • 13
    • 13
    • 13
    • 10
    • 9
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Sequenz
    GPRPQGATVS LWETVQKWRE YRRQCQRSLT EDPPPATDLF CNRTFDEYAC WPDGEPGSFV NVSCPWYLPW ASSVPQGHVY RFCTAEGLWL QKDNS
    Kreuzreaktivität
    Maus, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 22-116 of human GLP1R (NP_002053.3).
    Isotyp
    IgG
    Top Product
    Discover our top product GLP1R Primärantikörper
  • Applikationshinweise
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    Kommentare

    HIGH QUALITY

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Gao, Li, Li: "Exendin-4 promotes the osteogenic differentiation of osteoblasts via the Hedgehog/Gli1 signaling pathway." in: American journal of translational research, Vol. 10, Issue 1, pp. 315-324, (2018) (PubMed).

  • Target
    GLP1R (Glucagon-Like Peptide 1 Receptor (GLP1R))
    Andere Bezeichnung
    GLP1R (GLP1R Produkte)
    Synonyme
    GLP1R antikoerper, LOC100228311 antikoerper, GLP-1R antikoerper, GLP1Rc antikoerper, Glip antikoerper, RATGL1RCP antikoerper, glucagon like peptide 1 receptor antikoerper, glucagon-like peptide 1 receptor antikoerper, GLP1R antikoerper, Glp1r antikoerper
    Hintergrund
    This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants.,GLP1R,GLP-1,GLP-1-R,GLP-1R,Cancer,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Endocrine & Metabolism,Endocrine and metabolic diseases,Diabetes,Neuroscience,Cardiovascular,GLP1R
    Molekulargewicht
    53 kDa
    Gen-ID
    2740
    UniProt
    P43220
    Pathways
    Positive Regulation of Peptide Hormone Secretion, Hormone Transport, cAMP Metabolic Process, Feeding Behaviour
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