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GLUD1 Antikörper (AA 54-240)

GLUD1 Reaktivität: Human WB, IHC, IP, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6141157
  • Target Alle GLUD1 Antikörper anzeigen
    GLUD1 (Glutamate Dehydrogenase 1 (GLUD1))
    Bindungsspezifität
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 54-240
    Reaktivität
    • 36
    • 17
    • 16
    • 14
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 41
    • 9
    • 1
    Kaninchen
    Klonalität
    • 41
    • 10
    Polyklonal
    Konjugat
    • 29
    • 7
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GLUD1 Antikörper ist unkonjugiert
    Applikation
    • 31
    • 22
    • 18
    • 10
    • 10
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)
    Sequenz
    SEAVADREDD PNFFKMVEGF FDRGASIVED KLVEDLRTRE SEEQKRNRVR GILRIIKPCN HVLSLSFPIR RDDGSWEVIE GYRAQHSQHR TPCKGGIRYS TDVSVDEVKA LASLMTYKCA VVDVPFGGAK AGVKINPKNY TDNELEKITR RFTMELAKKG FIGPGIDVPA PDMSTGEREM SWIADTY
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 54-240 of human GLUD1 (NP_005262.1).
    Isotyp
    IgG
    Top Product
    Discover our top product GLUD1 Primärantikörper
  • Applikationshinweise
    WB,1:500 - 1:2000,IHC,1:100 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200
    Kommentare

    HIGH QUALITY

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    GLUD1 (Glutamate Dehydrogenase 1 (GLUD1))
    Andere Bezeichnung
    GLUD1 (GLUD1 Produkte)
    Hintergrund
    This gene encodes glutamate dehydrogenase, which is a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid-induced insulin secretion. It is allosterically activated by ADP and inhibited by GTP and ATP. Activating mutations in this gene are a common cause of congenital hyperinsulinism. Alternative splicing of this gene results in multiple transcript variants. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Related pseudogenes have been identified on chromosomes 10, 18 and X.,GLUD1,GDH,GDH1,GLUD,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Endocrine & Metabolism,Amino acid metabolism,GLUD1
    Molekulargewicht
    42 kDa/46 kDa/61 kDa
    Gen-ID
    2746
    UniProt
    P00367
    Pathways
    Positive Regulation of Peptide Hormone Secretion, Warburg Effekt
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