2010015D03Rik antikoerper, 2610111I01Rik antikoerper, 5330403M05Rik antikoerper, GTF3A antikoerper, TFIIIA antikoerper, gtf3a antikoerper, zgc:111799 antikoerper, AP2 antikoerper, general transcription factor III A antikoerper, general transcription factor IIIA antikoerper, general transcription factor 3A L homeolog antikoerper, general transcription factor IIIAa antikoerper, Gtf3a antikoerper, GTF3A antikoerper, gtf3a.L antikoerper, gtf3aa antikoerper
Hintergrund
The product of this gene is a zinc finger protein with nine Cis[2]-His[2] zinc finger domains. It functions as an RNA polymerase III transcription factor to induce transcription of the 5S rRNA genes. The protein binds to a 50 bp internal promoter in the 5S genes called the internal control region (ICR), and nucleates formation of a stable preinitiation complex. This complex recruits the TFIIIC and TFIIIB transcription factors and RNA polymerase III to form the complete transcription complex. The protein is thought to be translated using a non-AUG translation initiation site in mammals based on sequence analysis, protein homology, and the size of the purified protein.,GTF3A,AP2,TFIIIA,Epigenetics & Nuclear Signaling,Transcription Factors,GTF3A