HECTD1 Antikörper (AA 2518-2610)

Produktnummer ABIN6141706

Produktdetails anti-HECTD1 Antikörper

Target: HECTD1 (HECT Domain Containing 1 (HECTD1))

Bindungsspezifität: AA 2518-2610

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HECTD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: PGFLRFVRVL CGMSSDERKA FLQFTTGCST LPPGGLANLH PRLTVVRKVD ATDASYPSVN TCVHYLKLPE YSSEEIMRER LLAATMEKGF HLN

Kreuzreaktivität: Human

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 2518-2610 of human HECTD1 (NP_056197.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu HECTD1

Target: HECTD1 (HECT Domain Containing 1 (HECTD1))

Andere Bezeichnung: HECTD1 (HECTD1 Produkte)

Synonyme: RGD1561653 antikoerper, HECTD1 antikoerper, hectd1 antikoerper, MGC172681 antikoerper, A630086P08Rik antikoerper, AI844876 antikoerper, b2b327Clo antikoerper, opm antikoerper, HECT domain E3 ubiquitin protein ligase 1 antikoerper, HECT domain containing E3 ubiquitin protein ligase 1 antikoerper, Hectd1 antikoerper, HECTD1 antikoerper, hectd1 antikoerper

Hintergrund: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates 'Lys-63'-linked polyubiquitination of HSP90AA1 which leads to its intracellular localization and reduced secretion. Negatively regulating HSP90AA1 secretion in cranial mesenchyme cells may impair their emigration and may be essential for the correct development of the cranial neural folds and neural tube closure.,HECTD1,EULIR,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,Ubiquitin,HECTD1

Molekulargewicht: 289 kDa

Gen-ID: 25831

UniProt: Q9ULT8

Pathways: Tube Formation, SARS-CoV-2 Protein Interaktom, Phosphorylierungen bei SARS-CoV-2 Infektion