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EPAS1 Antikörper (AA 588-870)

Name: EPAS1 Antikörper (AA 588-870)
Brand: antibodies-online
SKU: ABIN6141764
Price: 580.8 EUR
Availability: InStock

EPAS1 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

Western blot analysis of extracts of various cell lines, using EP/HIF2α antibody (ABIN6127869, ABIN6141764, ABIN6141765 and ABIN6223457) at 1:1000 dilution. (EPAS1 Antikörper (AA 588-870))

Immunohistochemistry of paraffin-embedded human brain using EP/HIF2α Rabbit pAb (ABIN6127869, ABIN6141764, ABIN6141765 and ABIN6223457) at dilution of 1:100 (40x lens). (EPAS1 Antikörper (AA 588-870))

IHC

Immunofluorescence analysis of cells using EP/HIF2α antibody (ABIN6127869, ABIN6141764, ABIN6141765 and ABIN6223457). (EPAS1 Antikörper (AA 588-870))

Immunohistochemistry of paraffin-embedded human thyroid cancer using EP/HIF2α Rabbit pAb (ABIN6127869, ABIN6141764, ABIN6141765 and ABIN6223457) at dilution of 1:100 (40x lens). (EPAS1 Antikörper (AA 588-870))

IHC

4 Abbildungen

Produktnummer ABIN6141764

Datenblatt (PDF)

Target Alle EPAS1 Antikörper anzeigen

EPAS1 (Endothelial PAS Domain Protein 1 (EPAS1))
Bindungsspezifität
16

11

9

7

7

6

6

6

6

3

3

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
AA 588-870
Reaktivität
95

54

48

18

17

3

3

2

2

2

2

2

1

1

1

1

1

1
Human
Wirt
103

9

1

1
Kaninchen
Passende Sekundärantikörper
Klonalität
96

18
Polyklonal
Konjugat
54

12

7

5

5

4

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
Dieser EPAS1 Antikörper ist unkonjugiert
Applikation
87

44

30

21

14

13

13

13

12

10

4

4

4

2

1

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequenz

FQQQLESKKT EPEHRPMSSI FFDAGSKASL PPCCGQASTP LSSMGGRSNT QWPPDPPLHF GPTKWAVGDQ RTEFLGAAPL GPPVSPPHVS TFKTRSAKGF GARGPDVLSP AMVALSNKLK LKRQLEYEEQ AFQDLSGGDP PGGSTSHLMW KRMKNLRGGS CPLMPDKPLS ANVPNDKFTQ NPMRGLGHPL RHLPLPQPPS AISPGENSKS RFPPQCYATQ YQDYSLSSAH KVSGMASRLL GPSFESYLLP ELTRYDCEVN VPVLGSSTLL QGGDLLRALD QAT

Kreuzreaktivität

Human, Maus, Ratte

Produktmerkmale

Polyclonal Antibodies

Aufreinigung

Affinity purification

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 588-870 of human EPAS1/HIF2alpha (NP_001421.2).

Isotyp

IgG

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anti-Endothelial PAS Domain Protein 1 (EPAS1) (AA 26-347) antibody
EPAS1 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:100

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

-20 °C

Informationen zur Lagerung

Store at -20°C. Avoid freeze / thaw cycles.
Target

EPAS1 (Endothelial PAS Domain Protein 1 (EPAS1))

Andere Bezeichnung

EPAS1 (EPAS1 Produkte)

Synonyme

EPAS1 antikoerper, ECYT4 antikoerper, HIF2A antikoerper, HLF antikoerper, MOP2 antikoerper, PASD2 antikoerper, bHLHe73 antikoerper, HIF-2alpha antikoerper, HRF antikoerper, Hif2a antikoerper, bhlhe73 antikoerper, ecyt4 antikoerper, hif2 antikoerper, hif2a antikoerper, hif2alpha antikoerper, hlf antikoerper, mop2 antikoerper, pasd2 antikoerper, EPAS antikoerper, EPAS-1 antikoerper, endothelial PAS domain protein 1 antikoerper, endothelial PAS domain protein 1 L homeolog antikoerper, EPAS1 antikoerper, epas1 antikoerper, Epas1 antikoerper, epas1.L antikoerper

Hintergrund

This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4.,EPAS1,ECYT4,HIF2A,HLF,MOP2,PASD2,bHLHe73,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Invasion and Metastasis,Endocrine & Metabolism,Nucleotide metabolism,Molecular processes,Cardiovascular,Angiogenesis,Hypoxia,HIF,EPAS1

Molekulargewicht

96 kDa

Gen-ID

2034

UniProt

Q99814

Pathways

Signaling Events mediated by VEGFR1 and VEGFR2, Warburg Effekt