EPAS1 Antikörper (AA 588-870)

Produktnummer ABIN6141764

Produktdetails anti-EPAS1 Antikörper

Target: EPAS1 (Endothelial PAS Domain Protein 1 (EPAS1))

Bindungsspezifität: AA 588-870

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EPAS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequenz: FQQQLESKKT EPEHRPMSSI FFDAGSKASL PPCCGQASTP LSSMGGRSNT QWPPDPPLHF GPTKWAVGDQ RTEFLGAAPL GPPVSPPHVS TFKTRSAKGF GARGPDVLSP AMVALSNKLK LKRQLEYEEQ AFQDLSGGDP PGGSTSHLMW KRMKNLRGGS CPLMPDKPLS ANVPNDKFTQ NPMRGLGHPL RHLPLPQPPS AISPGENSKS RFPPQCYATQ YQDYSLSSAH KVSGMASRLL GPSFESYLLP ELTRYDCEVN VPVLGSSTLL QGGDLLRALD QAT

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 588-870 of human EPAS1/HIF2alpha (NP_001421.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu EPAS1

Target: EPAS1 (Endothelial PAS Domain Protein 1 (EPAS1))

Andere Bezeichnung: EPAS1 (EPAS1 Produkte)

Synonyme: EPAS1 antikoerper, ECYT4 antikoerper, HIF2A antikoerper, HLF antikoerper, MOP2 antikoerper, PASD2 antikoerper, bHLHe73 antikoerper, HIF-2alpha antikoerper, HRF antikoerper, Hif2a antikoerper, bhlhe73 antikoerper, ecyt4 antikoerper, hif2 antikoerper, hif2a antikoerper, hif2alpha antikoerper, hlf antikoerper, mop2 antikoerper, pasd2 antikoerper, EPAS antikoerper, EPAS-1 antikoerper, endothelial PAS domain protein 1 antikoerper, endothelial PAS domain protein 1 L homeolog antikoerper, EPAS1 antikoerper, epas1 antikoerper, Epas1 antikoerper, epas1.L antikoerper

Hintergrund: This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4.,EPAS1,ECYT4,HIF2A,HLF,MOP2,PASD2,bHLHe73,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Invasion and Metastasis,Endocrine & Metabolism,Nucleotide metabolism,Molecular processes,Cardiovascular,Angiogenesis,Hypoxia,HIF,EPAS1

Molekulargewicht: 96 kDa

Gen-ID: 2034

UniProt: Q99814

Pathways: Signaling Events mediated by VEGFR1 and VEGFR2, Warburg Effekt