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HNRNPA1 Antikörper (AA 1-372)

HNRNPA1 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6141896
  • Target Alle HNRNPA1 Antikörper anzeigen
    HNRNPA1 (Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1))
    Bindungsspezifität
    • 15
    • 8
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-372
    Reaktivität
    • 67
    • 52
    • 47
    • 19
    • 15
    • 9
    • 7
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    Human
    Wirt
    • 78
    • 5
    Kaninchen
    Klonalität
    • 68
    • 15
    Polyklonal
    Konjugat
    • 39
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser HNRNPA1 Antikörper ist unkonjugiert
    Applikation
    • 46
    • 27
    • 20
    • 15
    • 15
    • 14
    • 14
    • 7
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Sequenz
    MSKSESPKEP EQLRKLFIGG LSFETTDESL RSHFEQWGTL TDCVVMRDPN TKRSRGFGFV TYATVEEVDA AMNARPHKVD GRVVEPKRAV SREDSQRPGA HLTVKKIFVG GIKEDTEEHH LRDYFEQYGK IEVIEIMTDR GSGKKRGFAF VTFDDHDSVD KIVIQKYHTV NGHNCEVRKA LSKQEMASAS SSQRGRSGSG NFGGGRGGGF GGNDNFGRGG NFSGRGGFGG SRGGGGYGGS GDGYNGFGND GGYGGGGPGY SGGSRGYGSG GQGYGNQGSG YGGSGSYDSY NNGGGGGFGG GSGSNFGGGG SYNDFGNYNN QSSNFGPMKG GNFGGRSSGP YGGGGQYFAK PRNQGGYGGS SSSSSYGSGR RF
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-372 of human hnRNP A1 (NP_112420.1).
    Isotyp
    IgG
    Top Product
    Discover our top product HNRNPA1 Primärantikörper
  • Applikationshinweise
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
    Kommentare

    HIGH QUALITY

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Wei, Dai, Zhou, He, Yao, Zhao, Guo, Yang: "Oroxylin A activates PKM1/HNF4 alpha to induce hepatoma differentiation and block cancer progression." in: Cell death & disease, Vol. 8, Issue 7, pp. e2944, (2018) (PubMed).

    Wang, Fu, Chen, Wu, Fan, Li, Zhu, Jia, Ji, Wang, Wong, Hu, Hui: "SPSB1-mediated HnRNP A1 ubiquitylation regulates alternative splicing and cell migration in EGF signaling." in: Cell research, Vol. 27, Issue 4, pp. 540-558, (2017) (PubMed).

  • Target
    HNRNPA1 (Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1))
    Andere Bezeichnung
    HNRNPA1 (HNRNPA1 Produkte)
    Hintergrund
    This gene encodes a member of a family of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs), which are RNA-binding proteins that associate with pre-mRNAs in the nucleus and influence pre-mRNA processing, as well as other aspects of mRNA metabolism and transport. The protein encoded by this gene is one of the most abundant core proteins of hnRNP complexes and plays a key role in the regulation of alternative splicing. Mutations in this gene have been observed in individuals with amyotrophic lateral sclerosis 20. Multiple alternatively spliced transcript variants have been found. There are numerous pseudogenes of this gene distributed throughout the genome.,HNRNPA1,ALS19,ALS20,HNRPA1,HNRPA1L3,IBMPFD3,UP 1,hnRNP A1,hnRNP-A1,Epigenetics & Nuclear Signaling,RNA Binding,HNRNPA1
    Molekulargewicht
    29 kDa/34 kDa/38 kDa
    Gen-ID
    3178
    UniProt
    P09651
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