IFIT2 Antikörper (AA 273-472)

Produktnummer ABIN6142178

Produktdetails anti-IFIT2 Antikörper

Target: IFIT2 (Interferon-Induced Protein with Tetratricopeptide Repeats 2 (IFIT2))

Bindungsspezifität: AA 273-472

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IFIT2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: ALEYIPNNAY LHCQIGCCYR AKVFQVMNLR ENGMYGKRKL LELIGHAVAH LKKADEANDN LFRVCSILAS LHALADQYED AEYYFQKEFS KELTPVAKQL LHLRYGNFQL YQMKCEDKAI HHFIEGVKIN QKSREKEKMK DKLQKIAKMR LSKNGADSEA LHVLAFLQEL NEKMQQADED SERGLESGSL IPSASSWNGE

Kreuzreaktivität: Human

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 273-472 of human IFIT2 (NP_001538.4).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu IFIT2

Target: IFIT2 (Interferon-Induced Protein with Tetratricopeptide Repeats 2 (IFIT2))

Andere Bezeichnung: IFIT2 (IFIT2 Produkte)

Synonyme: G10P2 antikoerper, GARG-39 antikoerper, IFI-54 antikoerper, IFI-54K antikoerper, IFI54 antikoerper, IFIT-2 antikoerper, ISG-54 K antikoerper, ISG-54K antikoerper, ISG54 antikoerper, P54 antikoerper, cig42 antikoerper, wu:fb58d07 antikoerper, DKFZp468G198 antikoerper, AV302338 antikoerper, Ifi54 antikoerper, interferon induced protein with tetratricopeptide repeats 2 antikoerper, interferon-induced protein with tetratricopeptide repeats 2 antikoerper, interferon-induced protein with tetratricopeptide repeats 15 antikoerper, IFIT2 antikoerper, Ifit2 antikoerper, ifit15 antikoerper

Hintergrund: IFN-induced antiviral protein which inhibits expression of viral messenger RNAs lacking 2'-O-methylation of the 5' cap. The ribose 2'-O-methylation would provide a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Viruses evolved several ways to evade this restriction system such as encoding their own 2'-O-methylase for their mRNAs or by stealing host cap containing the 2'-O-methylation (cap snatching mechanism. Binds AU-rich viral RNAs, with or without 5' triphosphorylation, RNA-binding is required for antiviral activity. Can promote apoptosis.,IFIT2,G10P2,GARG-39,IFI-54,IFI-54K,IFI54,IFIT-2,ISG-54 K,ISG-54K,ISG54,P54,cig42,Epigenetics & Nuclear Signaling,RNA Binding,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microtubules,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,IFIT2

Molekulargewicht: 54 kDa

Gen-ID: 3433

UniProt: P09913