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IGF2R Antikörper (AA 2327-2491)

IGF2R Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6142247
  • Target Alle IGF2R Antikörper anzeigen
    IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))
    Bindungsspezifität
    • 16
    • 13
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2327-2491
    Reaktivität
    • 88
    • 36
    • 19
    • 8
    • 5
    • 3
    • 2
    • 1
    • 1
    Human
    Wirt
    • 67
    • 23
    Kaninchen
    Klonalität
    • 66
    • 24
    Polyklonal
    Konjugat
    • 46
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IGF2R Antikörper ist unkonjugiert
    Applikation
    • 34
    • 33
    • 28
    • 23
    • 13
    • 13
    • 13
    • 11
    • 8
    • 6
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Sequenz
    YKKERRETVI SKLTTCCRRS SNVSYKYSKV NKEEETDENE TEWLMEEIQL PPPRQGKEGQ ENGHITTKSV KALSSLHGDD QDSEDEVLTI PEVKVHSGRG AGAESSHPVR NAQSNALQER EDDRVGLVRG EKARKGKSSS AQQKTVSSTK LVSFHDDSDE DLLHI
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 2327-2491 of human Cation-independent M6PR (Cation-independent M6PR (IGF2R)) (NP_000867.2).
    Isotyp
    IgG
    Top Product
    Discover our top product IGF2R Primärantikörper
  • Applikationshinweise
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    Kommentare

    HIGH QUALITY

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))
    Andere Bezeichnung
    IGF2R (IGF2R Produkte)
    Synonyme
    CD222 antikoerper, CIMPR antikoerper, M6P-R antikoerper, MPR1 antikoerper, MPRI antikoerper, AI661837 antikoerper, CI-MPR antikoerper, M6P/IGF2R antikoerper, Mpr300 antikoerper, mpri antikoerper, cd222 antikoerper, cimpr antikoerper, m6p-r antikoerper, insulin like growth factor 2 receptor antikoerper, insulin-like growth factor 2 receptor antikoerper, IGF2R antikoerper, Igf2r antikoerper, igf2r antikoerper
    Hintergrund
    This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions, including in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with risk of hepatocellular carcinoma. The orthologous mouse gene is imprinted and shows exclusive expression from the maternal allele, however, imprinting of the human gene may be polymorphic, as only a minority of individuals showed biased expression from the maternal allele (PMID:8267611).,IGF2R,CD222,CI-M6PR,CIMPR,M6P-R,M6P/IGF2R,MPR 300,MPR1,MPR300,MPRI,Signal Transduction,Immunology & Inflammation,CD markers,Cell Intrinsic Innate Immunity Signaling Pathway,IGF2R
    Molekulargewicht
    274 kDa
    Gen-ID
    3482
    UniProt
    P11717
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