ALS antikoerper, Albs antikoerper, mKIAA4111 antikoerper, Als antikoerper, insulin like growth factor binding protein acid labile subunit antikoerper, insulin like growth factor binding protein acid labile subunit L homeolog antikoerper, insulin-like growth factor binding protein, acid labile subunit antikoerper, IGFALS antikoerper, igfals.L antikoerper, Igfals antikoerper
Hintergrund
The protein encoded by this gene is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this gene are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty. Three transcript variants encoding two different isoforms have been found for this gene.,IGFALS,ACLSD,ALS,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Cardiovascular,Blood,Serum Proteins,IGFALS