ING3 Antikörper (AA 1-92)
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- Target Alle ING3 Antikörper anzeigen
- ING3 (Inhibitor of Growth Family, Member 3 (ING3))
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Bindungsspezifität
- AA 1-92
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ING3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- MLYLEDYLEM IEQLPMDLRD RFTEMREMDL QVQNAMDQLE QRVSEFFMNA KKNKPEWREE QMASIKKDYY KALEDADEKV QLANQIYDLQ HF
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
- Polyclonal Antibodies
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-92 of human ING3 (NP_938008.1).
- Isotyp
- IgG
- Top Product
- Discover our top product ING3 Primärantikörper
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- Applikationshinweise
- WB,1:500 - 1:2000
- Kommentare
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HIGH QUALITY
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- ING3 (Inhibitor of Growth Family, Member 3 (ING3))
- Andere Bezeichnung
- ING3 (ING3 Produkte)
- Hintergrund
- The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Two alternatively spliced transcript variants encoding different isoforms have been observed.,ING3,Eaf4,ING2,MEAF4,p47ING3,Epigenetics & Nuclear Signaling,Cancer,Tumor suppressors,ING3
- Molekulargewicht
- 11 kDa/46 kDa
- Gen-ID
- 54556
- UniProt
- Q9NXR8
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